National Center for Nanoscience and Technology, Beijing 100190, China.
Angew Chem Int Ed Engl. 2012 May 29;51(22):5296-307. doi: 10.1002/anie.201104904. Epub 2012 Apr 13.
Over millions of years, complex processes of intelligent control have evolved in nature. Learning from nature is a continuing theme in the development of smart materials and intelligent systems. For example, biological nanochannels, which are typically ion channels, play a very important role in basic biochemical processes in cells. Inspired by ion channels, in which the components are asymmetrically distributed between the membrane surfaces, the generation of biomimetic smart nanochannels is a broad and varied scientific research field. The design and development of new biomimetic channels includes the use of different shapes of channels, different stimuli-responsive molecules, and different symmetric/asymmetric modification methods. In this Minireview, we summarize recent developments in building functional nanochannels by applying various symmetric and asymmetric modifications.
在数百万年的时间里，自然界中已经进化出了复杂的智能控制过程。从自然中学习是智能材料和智能系统发展的一个持续主题。例如，生物纳米通道通常是离子通道，在细胞的基本生化过程中起着非常重要的作用。受离子通道的启发，其中的组件在膜表面之间不对称分布，仿生智能纳米通道的产生是一个广泛而多样的科学研究领域。新型仿生通道的设计和开发包括使用不同形状的通道、不同的刺激响应分子以及不同的对称/不对称修饰方法。在这篇综述中，我们总结了通过应用各种对称和不对称修饰来构建功能纳米通道的最新进展。
