Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.
Trends Biotechnol. 2011 Dec;29(12):607-14. doi: 10.1016/j.tibtech.2011.07.006. Epub 2011 Aug 25.
Through recent advances in nanotechnology and molecular engineering, biomimetics - the development of synthetic systems that imitate biological structures and processes - is now emerging at the nanoscale. In this review, we explore biomimetic nanopores and nanochannels. Biological systems are full of nano-scale channels and pores that inspire us to devise artificial pores that demonstrate molecular selectivity or other functional advantages. Moreover, with a biomimetic approach, we can also study biological pores, through bottom-up engineering approaches whereby constituent components can be investigated outside the complex cellular environment.
通过最近在纳米技术和分子工程方面的进展,仿生学——开发模仿生物结构和过程的合成系统——现在正在纳米尺度上出现。在这篇综述中,我们探讨了仿生纳米孔和纳米通道。生物系统充满了纳米尺度的通道和孔,这启发我们设计出展示分子选择性或其他功能优势的人工孔。此外,通过仿生方法,我们还可以通过自下而上的工程方法来研究生物孔,从而在复杂的细胞环境之外研究组成成分。