颈部色素性黑色素性神经鞘瘤：2例报告并文献复习
Pigmented Melanotic Schwannoma of the Neck: Report of 2 Cases and Review of the Literature.
作者信息
Topf Michael C, Pham Quang H, D'Souza Jill N, Chaskes Mark, Tuluc Madalina, Cognetti David M, Luginbuhl Adam J
机构信息
1 Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
2 Department of Otolaryngology-Head and Neck Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.
出版信息
Ear Nose Throat J. 2019 Feb;98(2):102-106. doi: 10.1177/0145561319826542. Epub 2019 Feb 13.
BACKGROUND
: Melanotic schwannoma is a rare tumor with indeterminate biologic behavior and varying treatment recommendations.
METHODS
: We report 2 cases of pigmented melanotic schwannoma of the head and neck and perform literature review. The pathologic and immunohistochemical characteristics of melanotic schwannoma are reviewed.
RESULTS
: Two cases of melanotic schwannoma are presented. Both cases underwent surgical resection with one patient receiving adjuvant radiation therapy.
CONCLUSIONS
: Melanotic schwannoma is a rare nerve sheath tumor that is frequently mistaken for malignant melanoma. We describe 2 cases of pigmented melanotic schwannoma of the head and neck with different presentations and review the histopathological and immunohistochemical features.
背景
黑色素性神经鞘瘤是一种罕见肿瘤，其生物学行为不确定，治疗建议也各不相同。
方法
我们报告2例头颈部色素沉着性黑色素性神经鞘瘤病例并进行文献复习。对黑色素性神经鞘瘤的病理及免疫组化特征进行回顾。
结果
呈现2例黑色素性神经鞘瘤病例。两例均接受了手术切除，其中1例患者接受了辅助放疗。
结论
黑色素性神经鞘瘤是一种罕见的神经鞘瘤，常被误诊为恶性黑色素瘤。我们描述了2例头颈部色素沉着性黑色素性神经鞘瘤，其表现各异，并回顾了组织病理学和免疫组化特征。
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