Jiangsu Key Laboratory of 3D Printing Equipment and Manufacturing, School of Electrical and Automation Engineering, Nanjing Normal University, Nanjing, China.
Nanjing Institute of Intelligent Advanced Equipment Industry Co., Ltd., Nanjing, China.
J Transl Med. 2019 Mar 18;17(1):89. doi: 10.1186/s12967-019-1834-2.
Artificial meniscal implants can be used to replace a severely injured meniscus after meniscectomy and restore the normal functionality of a knee joint. The aim of this paper was to design porous meniscal implants and assess their biomechanical properties.
Finite element simulations were conducted on eight different cases including intact healthy knees, knee joints with solid meniscal implants, and knee joints with meniscal implants with two types of triply periodic minimal surfaces. Compression stresses, shear stresses, and characteristics of stress concentrated areas were evaluated using an axial compressive load of 1150 N and an anterior load of 350 N.
Compared to the solid meniscal implant, the proposed porous meniscal implant produced lower levels of compression and shear stresses on the cartilage, which facilitated the cartilage to retain a semilunar characteristic similar to the natural meniscus. Moreover, both compression and shear stresses on the artificial cartilage were found to be sensitive to the pore properties of the meniscal implant. The meniscal implants with primitive surfaces (porosity: 41%) showed a better performance in disseminating stresses within the knee joint.
The present commercial meniscal implant has the problem of equivalent biomechanical properties compared to natural menisci. The main advantage of the proposed porous structure is that it can be used to prevent excessive compression and shear stresses on the articular cartilages. This structure has advantages both in terms of mechanics and printability, which can be beneficial for future clinical applications.
人工半月板植入物可用于半月板切除术后替代严重受损的半月板,并恢复膝关节的正常功能。本文旨在设计多孔半月板植入物并评估其生物力学性能。
对 8 种不同情况进行了有限元模拟,包括完整的健康膝关节、带有实心半月板植入物的膝关节和带有两种类型的三重周期性最小曲面的半月板植入物的膝关节。使用 1150 N 的轴向压缩载荷和 350 N 的前向载荷评估压缩应力、剪切应力和应力集中区的特征。
与实心半月板植入物相比,所提出的多孔半月板植入物在软骨上产生的压缩和剪切应力较低,这有助于软骨保持类似于天然半月板的半月形特征。此外,人工软骨上的压缩和剪切应力都对半月板植入物的孔特性敏感。具有原始表面(孔隙率:41%)的半月板植入物在膝关节内分散应力方面表现出更好的性能。
目前的商业半月板植入物在与天然半月板相比具有等效的生物力学性能的问题。所提出的多孔结构的主要优点是可以防止关节软骨上的过度压缩和剪切应力。这种结构在力学和可打印性方面都有优势,这对未来的临床应用可能是有益的。