Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
Department of Statistical Sciences, University of Padova, Padova, Italy.
Clin Otolaryngol. 2019 Jul;44(4):541-548. doi: 10.1111/coa.13329. Epub 2019 Apr 21.
Nasal obstruction is the most common symptom in nasal diseases. It can be evaluated objectively, that is by means of peak nasal inspiratory flow (PNIF) measures and/or subjectively by means of validated questionnaires. However, it has been reported that there is a lack of reliable correlation between subjective and objective measurements of nasal obstruction. The aim of the present study was to evaluate the correlation between PNIF measurements and the subjective sensation of nasal obstruction measured by means of a visual analogue scale (VAS) in a large population of consecutive rhinologic patients.
Prospective clinical study.
Tertiary rhinological referral centre.
A total of 641 consecutive subjects were enrolled. Visual analogue scale and PNIF were performed to assess nasal obstruction. Nasal septal deviation was classified according to Mladina classification, and its severity was assessed using three levels of severity.
Although weak, there was a significant negative correlation (r = -0.13, P = 0.001) between PNIF and VAS. Dividing the population in those affected by nasal septal deviation (NSD) and those affected by chronic rhinosinusitis (CRS), a week negative correlation between PNIF and VAS was again confirmed in both groups (r = -0.208, P = 0.006 for NSD and r = -0.13, P = 0.04 for CRS). Peak nasal inspiratory flow and VAS were also evaluated according to the grade of polyps and the type and level of septal deviation.
Visual analogue scale and PNIF significantly correlated, although with a low degree, in a large population of rhinologic patients. Peak nasal inspiratory flow, being cheap and simple to use, could be a good candidate to assist clinicians dealing with "airway" diseases in their daily clinical practice in order to provide comprehensive information on nasal function. Peak nasal inspiratory flow can in fact give some important rough insights on VAS, but these measurements cannot be alternative to each other.
鼻塞是鼻部疾病最常见的症状。它可以通过鼻吸气峰流速(PNIF)测量值进行客观评估,或者通过经验证的问卷进行主观评估。然而,据报道,主观和客观测量鼻塞之间缺乏可靠的相关性。本研究旨在评估在大量连续的鼻科患者中,PNIF 测量值与通过视觉模拟量表(VAS)评估的主观鼻塞感觉之间的相关性。
前瞻性临床研究。
三级鼻科转诊中心。
共纳入 641 例连续患者。通过 VAS 和 PNIF 评估鼻塞。鼻中隔偏曲按 Mladina 分类进行分类,并使用三个严重程度水平评估其严重程度。
尽管相关性较弱,但 PNIF 与 VAS 之间存在显著的负相关(r=-0.13,P=0.001)。将人群分为鼻中隔偏曲(NSD)和慢性鼻-鼻窦炎(CRS)两组,两组均再次证实 PNIF 与 VAS 之间存在负相关(NSD 组 r=-0.208,P=0.006;CRS 组 r=-0.13,P=0.04)。还根据息肉的程度、鼻中隔偏曲的类型和程度评估了 PNIF 和 VAS。
在大量的鼻科患者中,VAS 和 PNIF 显著相关,尽管相关性较低。PNIF 廉价且易于使用,可作为辅助临床医生在日常临床实践中处理“气道”疾病的良好候选者,以便提供有关鼻腔功能的综合信息。PNIF 实际上可以提供一些关于 VAS 的重要的大致见解,但这些测量值不能相互替代。