Pendolino Alfonso Luca, Unadkat Samit, Cheong Ryan Chin Taw, Patel Ankit, Ferreira Joshua, Scarpa Bruno, Andrews Peter J
Department of ENT, Royal National ENT & Eastman Dental Hospitals, London WC1E 6DG, UK.
Ear Institute, University College London (UCL), London WC1X 8EE, UK.
Diagnostics (Basel). 2024 Aug 21;14(16):1820. doi: 10.3390/diagnostics14161820.
Nasal obstruction is a frequent problem amongst patients with sleep-disordered breathing (SDB). Radiofrequency of the inferior turbinates (RFIT) is commonly utilized for inferior turbinate (IT) reduction but its effectiveness in SDB patients remains unproven. We aim to evaluate long-term objective and subjective nasal, olfactory and sleep outcomes following RFIT in SDB patients.
Patients were assessed at baseline (T0) and at 3 months (T1), 6 months (T2) and 12 months (T3) following RFIT. At T0, T1, T2 and T3, the patients underwent objective assessments of their nasal airways and smell function and an evaluation of their quality-of-life, sinonasal, olfactory and sleep symptoms. Sleep studies were carried out at T0 and T2.
Seventeen patients (with a median age of 42 years) underwent RFIT. A statistically significant objective and subjective improvement of the patients' nasal airways was demonstrated at T1. No other statistically significant changes were observed in the patients' nasal airways, smell, sleep study parameters or patient-reported outcomes at the other follow-ups. A multivariate analysis confirmed a statistically significant influence of age (older), sex (male), a higher BMI, the presence of septal deviation and the presence of allergic rhinitis in some of the studies' parameters. A statistically significant objective and subjective improvement of the patients' nasal airways was confirmed in the fitted model when considering the influence of the available variables.
Our study confirms that the benefits of RFIT alone in SDB patients are limited and possibly only in the short-term period. Patient-related variables can potentially influence the final outcomes.
鼻塞是睡眠呼吸障碍(SDB)患者中常见的问题。下鼻甲射频消融术(RFIT)常用于下鼻甲(IT)缩小,但在SDB患者中的有效性仍未得到证实。我们旨在评估SDB患者接受RFIT后的长期客观和主观鼻腔、嗅觉及睡眠结局。
在RFIT前(T0)以及术后3个月(T1)、6个月(T2)和12个月(T3)对患者进行评估。在T0、T1、T2和T3时,对患者的鼻气道和嗅觉功能进行客观评估,并对其生活质量、鼻窦、嗅觉和睡眠症状进行评估。在T0和T2时进行睡眠研究。
17例患者(中位年龄42岁)接受了RFIT。在T1时,患者的鼻气道在客观和主观上有统计学意义的改善。在其他随访中,患者的鼻气道、嗅觉、睡眠研究参数或患者报告的结局未观察到其他有统计学意义的变化。多因素分析证实,在某些研究参数中,年龄(较大)、性别(男性)、较高的体重指数、鼻中隔偏曲的存在以及过敏性鼻炎的存在有统计学意义的影响。在考虑可用变量的影响时,拟合模型中证实了患者鼻气道在客观和主观上有统计学意义的改善。
我们的研究证实,单独的RFIT对SDB患者的益处有限,可能仅在短期内有效。与患者相关的变量可能会影响最终结局。