Varesio L, Landolfo S, Cavallo G
Folia Biol (Praha). 1978;24(4):264-9.
Spleen cells from mice immunized with SRBC were transferred, at various times after immunization, to non-irradiated and lethally irradiated syngeneic recipients. The PFC kinetics and anti-SRBC antibody titres were followed in various groups of mice. Similar results were obtained both in non-irradiated and lethally irradiated recipients, showing that after the transfer: a) PFC proliferation was blocked, b) PFC blocking was unrelated to their maturation stage, c) resting PFC were still able to synthesize antibodies, d) blocking activity was radio-resistant.
用绵羊红细胞(SRBC)免疫的小鼠脾脏细胞,在免疫后的不同时间,被转移到未受照射和受到致死剂量照射的同基因受体小鼠体内。对不同组小鼠的空斑形成细胞(PFC)动力学和抗SRBC抗体滴度进行了跟踪观察。在未受照射和受到致死剂量照射的受体小鼠中均得到了相似的结果,表明在细胞转移后:a)PFC增殖受到阻断;b)PFC阻断与其成熟阶段无关;c)静止的PFC仍能够合成抗体;d)阻断活性具有抗辐射性。