Interference between two immune responses. II.--Conferrability by the serum of the influences exerted by a response to horse RBC on the subsequent response to sheep RBC in the mouse.

Serum taken from mice responding to HoRBC and given to syngeneic mice influences the kinetics of a subsequent anti-SRBC response. The serum taken at the 36th of the anti-HoRBC response exerts after transfer an accelerating effect on the anti-SRBC response while this of the 7th day has an inhibitory effect. Both effects are especially demonstrative on mice irradiated and restored with spleen cells from a single donor because of the low variation coefficient of their anti-SRBC response.