Yoldemir T, Garibova N, Atasayan K
Department of Obstetrics and Gynaecology, Marmara University Hospital , Istanbul , Turkey.
Obstetrics and Gynaecology Clinic, Baku Medical Center , Baku , Azerbaijan.
Climacteric. 2019 Oct;22(5):472-477. doi: 10.1080/13697137.2019.1580256. Epub 2019 Mar 20.
The aim of this study is to determine the association between sexual dysfunction and metabolic syndrome (MS) among Turkish postmenopausal women : In total, 290 postmenopausal women between the ages of 50 and 70 years and 265 premenopausal women between the ages of 30 and 49 years who applied to Menopause and Gynecology Clinics at Marmara University-affiliated Pendik Education and Research Hospital, Istanbul, Turkey were included in this prospective survey. Sexual function was assessed using the Female Sexual Function Index (FSFI). A FSFI total score of <26.5 was suggestive of sexual dysfunction. MS was assessed by the National Cholesterol Education Program Adult Treatment Panel III criteria. Sexual dysfunction prevalence among postmenopausal women was 64.6% in relation to 42.1% in premenopausal women ( = 0.001). MS prevalence was 13.5% among premenopausal women and 15.5% among postmenopausal women ( = 0.57). The total FSFI score and each score in the desire, arousal, lubrication, orgasm, satisfaction, and dyspareunia domains of the FSFI did not differ between premenopausal and postmenopausal women, regarding the MS status. In the premenopausal group, 45.7% of women without MS and 37% of women with MS had lower sexual dysfunction ( = 0.40); whereas in the postmenopausal group, 62.2% of women without MS and 77.4% of women with MS had lower sexual function ( = 0.22). In our study population, the rate of sexual dysfunction increased in postmenopausal women in contrast to premenopausal women. The MS status did not make a difference in terms of sexual dysfunction either in premenopausal or postmenopausal women. Since our survey was conducted in a tertiary medical center which gave medical care service to women from middle and low socioeconomic classes, our results should be confirmed by a large multicenter survey enrolling women from all different socioeconomic classes.
本研究的目的是确定土耳其绝经后女性性功能障碍与代谢综合征（MS）之间的关联：共有290名年龄在50至70岁之间的绝经后女性以及265名年龄在30至49岁之间的绝经前女性纳入了这项前瞻性调查，这些女性均前往土耳其伊斯坦布尔马尔马拉大学附属彭迪克教育与研究医院的更年期与妇科诊所就诊。使用女性性功能指数（FSFI）评估性功能。FSFI总分<26.5提示性功能障碍。采用美国国家胆固醇教育计划成人治疗小组第三次报告的标准评估MS。绝经后女性性功能障碍患病率为64.6%，而绝经前女性为42.1%（P = 0.001）。绝经前女性MS患病率为13.5%，绝经后女性为15.5%（P = 0.57）。就MS状态而言，绝经前和绝经后女性的FSFI总分以及FSFI在性欲、性唤起、润滑、性高潮、满意度和性交疼痛领域的各项得分均无差异。在绝经前组中，无MS的女性中有45.7%以及有MS的女性中有37%性功能障碍发生率较低（P = 0.40）；而在绝经后组中，无MS的女性中有62.2%以及有MS的女性中有77.4%性功能较低（P = 0.22）。在我们的研究人群中，与绝经前女性相比，绝经后女性性功能障碍发生率有所增加。MS状态在绝经前或绝经后女性的性功能障碍方面均无差异。由于我们的调查是在一家为中低收入社会经济阶层女性提供医疗服务的三级医疗中心进行的，我们的结果应由一项纳入所有不同社会经济阶层女性的大型多中心调查加以证实。
