Juliato Cássia Raquel Teatin, Melotti Iane Glauce Ribeiro, Junior Luiz Carlos Santos, Britto Luiz Gustavo Oliveira, Riccetto Cássio Luiz Zanettini
Department of Obstetrics and Gynecology, School of Medicine, University of Campinas (UNICAMP), Campinas, Brazil.
School of Medicine, University of Campinas (UNICAMP), Campinas, Brazil.
J Sex Med. 2017 Jul;14(7):904-909. doi: 10.1016/j.jsxm.2017.05.005. Epub 2017 Jun 15.
Several studies have associated overactive bladder (OAB) with female sexual dysfunction (FSD); however, there are no reports using a quantitative approach to measure OAB severity and to relate OAB to the risk of FSD.
To evaluate women with OAB and to correlate the severity of their urinary symptoms with their sexual function.
This cross-sectional study included 267 women older than 18 years with untreated OAB. All subjects completed the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and the Female Sexual Function Index (FSFI).
Linear regression was used to analyze the association between variables and the numeric FSFI score, and categorical FSFI scores were analyzed using logistic regression. Spearman rank correlation coefficient was used to assess the correlation between ICIQ-OAB results and the different FSFI domains. The significance level was 5%.
Subjects' mean age was 50.2 ± 11.9 years. Most women were married, had at least three children, and were postmenopausal (54.3%). Mean FSFI total score was 19.2 ± 9.8. For menopausal status, 65.6% of premenopausal women had a risk for FSD vs 86.2% of postmenopausal women. Mean ICIQ-OAB score was 10 ± 3.17. Postmenopausal women had the following risk factors statistically associated with sexual dysfunction: age, ICIQ score, and marital status. For these women, greater OAB severity, especially those with urgency and/or urge incontinence, was associated with worse scores in the arousal, lubrication, orgasm, and sexual pain domains. However, there was no statistically significant association for premenopausal women.
Health professionals have to pay attention to OAB in women because of the greater risk for FSD in these patients.
The strength was using a quantitative approach to measure OAB severity in a larger population. Limitations include a convenience sample with no power calculation; exclusion of women who did not have sexual intercourse in the past month; unmeasured distress caused by sexual disorders; and the impossibility of establishing causality between OAB and sexual dysfunction.
Women with OAB frequently have a risk for sexual dysfunction. In the postmenopausal group, women with scores indicating severe OAB had worse sexual function, mainly in the arousal, lubrication, orgasm, pain, and total domains. Juliato CRT, Melotti IGR, Junior LCS, et al. Does the Severity of Overactive Bladder Symptoms Correlate With Risk for Female Sexual Dysfunction? J Sex Med 2017;14:904-909.
多项研究已将膀胱过度活动症（OAB）与女性性功能障碍（FSD）联系起来；然而，尚无使用定量方法来衡量OAB严重程度并将OAB与FSD风险相关联的报告。
评估患有OAB的女性，并将其泌尿系统症状的严重程度与性功能相关联。
这项横断面研究纳入了267名年龄超过18岁的未经治疗的OAB女性。所有受试者均完成了《国际尿失禁咨询委员会膀胱过度活动症问卷》（ICIQ - OAB）和《女性性功能指数》（FSFI）。
采用线性回归分析变量与FSFI数值评分之间的关联，使用逻辑回归分析FSFI分类评分。采用Spearman等级相关系数评估ICIQ - OAB结果与不同FSFI领域之间的相关性。显著性水平为5%。
受试者的平均年龄为50.2±11.9岁。大多数女性已婚，至少育有三个孩子，且处于绝经后状态（54.3%）。FSFI总分平均为19.2±9.8。对于绝经状态，65.6%的绝经前女性存在FSD风险，而绝经后女性为86.2%。ICIQ - OAB平均评分为10±3.17。绝经后女性具有以下与性功能障碍在统计学上相关的危险因素：年龄、ICIQ评分和婚姻状况。对于这些女性，OAB严重程度越高，尤其是那些有尿急和/或急迫性尿失禁的女性，在性唤起、润滑、性高潮和性交疼痛领域的评分越差。然而，绝经前女性之间没有统计学上的显著关联。
由于这些患者发生FSD的风险更高，卫生专业人员必须关注女性的OAB。
优点是在更大规模人群中使用定量方法来衡量OAB严重程度。局限性包括便利样本且未进行功效计算；排除过去一个月没有性行为的女性；未测量性功能障碍引起的痛苦；以及无法确定OAB与性功能障碍之间的因果关系。
患有OAB的女性经常存在性功能障碍风险。在绝经后组中，OAB评分表明严重的女性性功能较差，主要在性唤起、润滑、性高潮、疼痛和总体领域。Juliato CRT、Melotti IGR、Junior LCS等。膀胱过度活动症症状的严重程度与女性性功能障碍风险相关吗？《性医学杂志》2017；14：904 - 909。
