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术前心脏 CT 的三尖瓣环直径和右心室容积可预测行三尖瓣手术的患者术后右心室功能障碍。

Tricuspid annular diameter and right ventricular volume on preoperative cardiac CT can predict postoperative right ventricular dysfunction in patients who undergo tricuspid valve surgery.

机构信息

Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Republic of Korea.

Department of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Republic of Korea.

出版信息

Int J Cardiol. 2019 Aug 1;288:44-50. doi: 10.1016/j.ijcard.2019.03.002. Epub 2019 Mar 5.

DOI:10.1016/j.ijcard.2019.03.002
PMID:30890274
Abstract

BACKGROUND

We investigated the predictive value of preoperative computed tomography (CT)-derived tricuspid annular and right ventricular (RV) parameters for postoperative RV dysfunction in patients undergoing tricuspid valve (TV) surgery.

METHODS

We retrospectively reviewed clinical, transthoracic echocardiography (TTE), and CT data of 100 consecutive patients who underwent cardiac CT and subsequently received TV surgery. Preoperative cardiac CT and TTE parameters were analyzed, including TV annulus diameter and RV size. Univariate and multivariate logistic regression analyses were performed to identify significant predictors for postoperative RV dysfunction, both in the entire study population and in the subgroup of patients without preoperative RV dysfunction.

RESULTS

Postoperative RV dysfunction occurred in 46% of all patients. In the multivariate logistic regression analysis, longer TV annulus diameter (>29.3 mm/m on four-chamber view; (odds ratio [OR] 3.56, 95% confidence interval [CI] 1.13-11.24), larger RV volume (RV end-diastolic volume/body surface area > 128.8 ml/m) on CT (OR 3.85, 95% CI 1.24-11.98) and presence of preoperative RV dysfunction on TTE (OR 11.96, 95% CI 2.8-50.99) were independent predictors for postoperative RV dysfunction in the entire study population (P < 0.05). Among patients without preoperative RV dysfunction, longer TV annulus diameter (OR 4.02, 95% CI 1.20-13.41) and larger RV volume on CT (OR 6.09, 95% CI 1.87-19.80) were independent predictors for postoperative RV dysfunction (P < 0.05).

CONCLUSIONS

Preoperative assessment of cardiac CT imaging-based TV annular diameter and RV volume can provide independent information for predicting postoperative RV dysfunction in patients undergoing TV surgery.

摘要

背景

我们研究了术前计算机断层扫描(CT)得出的三尖瓣环和右心室(RV)参数对接受三尖瓣(TV)手术患者术后 RV 功能障碍的预测价值。

方法

我们回顾性分析了 100 例连续接受心脏 CT 检查并随后接受 TV 手术的患者的临床、经胸超声心动图(TTE)和 CT 数据。分析了术前心脏 CT 和 TTE 参数,包括 TV 瓣环直径和 RV 大小。对所有患者和术前无 RV 功能障碍患者亚组进行单因素和多因素逻辑回归分析,以确定术后 RV 功能障碍的显著预测因素。

结果

所有患者中有 46%出现术后 RV 功能障碍。多因素逻辑回归分析显示,TV 瓣环直径较长(四腔心视图>29.3mm/m;(优势比[OR] 3.56,95%置信区间[CI] 1.13-11.24),RV 容积较大(CT 上 RV 舒张末期容积/体表面积>128.8ml/m)(OR 3.85,95%CI 1.24-11.98)和术前 TTE 存在 RV 功能障碍(OR 11.96,95%CI 2.8-50.99)是整个研究人群术后 RV 功能障碍的独立预测因素(P<0.05)。在术前无 RV 功能障碍的患者中,TV 瓣环直径较长(OR 4.02,95%CI 1.20-13.41)和 CT 上 RV 容积较大(OR 6.09,95%CI 1.87-19.80)是术后 RV 功能障碍的独立预测因素(P<0.05)。

结论

术前心脏 CT 成像评估 TV 瓣环直径和 RV 容积可为接受 TV 手术的患者预测术后 RV 功能障碍提供独立信息。

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