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精神神经科学中的挑战与机遇

Challenges and Opportunities in Psychiatric Neuroscience.

作者信息

Gordon Joshua A, Frost Bellgowan Julie A, Lawhorn Collene, Scheinert Rachel B

机构信息

National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA.

出版信息

Cold Spring Harb Symp Quant Biol. 2018;83:1-8. doi: 10.1101/sqb.2018.83.037523. Epub 2019 Mar 19.

DOI:10.1101/sqb.2018.83.037523
PMID:30890580
Abstract

Psychiatry faces a number of challenges as a field. These include the high individual and societal costs of mental illnesses, overlapping and heterogeneous diagnoses, a complete lack of biomarkers, and treatments that, although efficacious for some, leave many without adequate relief. On the other hand, scientific and technical advances present considerable opportunities, especially in genomics, computational and theoretical approaches, and neural circuit technologies. The National Institute of Mental Health is committed to taking advantage of these opportunities to address the challenges of psychiatry, in the service of achieving our mission of transforming the understanding and treatment of mental illnesses.

摘要

作为一个领域,精神病学面临着诸多挑战。这些挑战包括精神疾病给个人和社会带来的高昂代价、诊断的重叠和异质性、完全缺乏生物标志物,以及一些治疗方法虽然对部分患者有效,但仍有许多患者无法得到充分缓解。另一方面,科学技术的进步带来了相当多的机遇,尤其是在基因组学、计算和理论方法以及神经回路技术方面。美国国立精神卫生研究所致力于利用这些机遇来应对精神病学的挑战,以实现我们转变对精神疾病的理解和治疗方式的使命。

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