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Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.获得性再生障碍性贫血男性中缺乏HLA - B5401的造血干祖细胞的造血逃逸
Haematologica. 2019 Oct;104(10):e447-e450. doi: 10.3324/haematol.2018.210856. Epub 2019 Mar 19.
2
Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia.在再生障碍性贫血中，缺乏 HLA 的造血干细胞通过无驱动突变实现持续的克隆性造血。
Blood Adv. 2018 May 8;2(9):1000-1012. doi: 10.1182/bloodadvances.2017013953.
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Epigenetic and microenvironmental alterations in bone marrow associated with ROS in experimental aplastic anemia.实验性再生障碍性贫血中与 ROS 相关的骨髓中表观遗传和微环境的改变。
Eur J Cell Biol. 2018 Jan;97(1):32-43. doi: 10.1016/j.ejcb.2017.11.003. Epub 2017 Nov 22.
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Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia.获得性再生障碍性贫血中与拷贝数中性 6pLOH 相关的 HLA 等位基因频繁缺失。
Blood. 2011 Dec 15;118(25):6601-9. doi: 10.1182/blood-2011-07-365189. Epub 2011 Sep 30.
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Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.iPSC 衍生的再生障碍性贫血造血干细胞的造血作用可逃避细胞毒性 T 细胞的攻击。
Blood Adv. 2018 Feb 27;2(4):390-400. doi: 10.1182/bloodadvances.2017013342.
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[Immunologically escaped hematopoiesis caused by HLA allelic loss in patients with aplastic anemia].再生障碍性贫血患者中由HLA等位基因缺失引起的免疫逃逸造血
Rinsho Ketsueki. 2012 Jul;53(7):651-7.
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Aplastic anemia, cellular and molecular aspects.再生障碍性贫血的细胞和分子发病机制。
Cell Biol Int. 2021 Dec;45(12):2395-2402. doi: 10.1002/cbin.11689. Epub 2021 Aug 27.
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SWI/SNF subunit expression heterogeneity in human aplastic anemia stem/progenitors.人类再生障碍性贫血干/祖细胞中SWI/SNF亚基表达的异质性
Exp Hematol. 2018 Jun;62:39-44.e2. doi: 10.1016/j.exphem.2018.03.005. Epub 2018 Mar 27.
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[Significance of clonal hematopoiesis in patients with acquired aplastic anemia].[克隆性造血在获得性再生障碍性贫血患者中的意义]
Rinsho Ketsueki. 2013 Apr;54(4):336-42.
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Hematopoietic stem progenitor cells lacking HLA differ from those lacking GPI-anchored proteins in the hierarchical stage and sensitivity to immune attack in patients with acquired aplastic anemia.在获得性再生障碍性贫血患者中，缺乏 HLA 的造血干细胞祖细胞与缺乏 GPI 锚定蛋白的造血干细胞祖细胞在分级阶段和对免疫攻击的敏感性上存在差异。
Leukemia. 2021 Nov;35(11):3257-3267. doi: 10.1038/s41375-021-01202-8. Epub 2021 Apr 6.
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Interferon-γ-mediated selective inhibition of hematopoiesis and the clonal advantage of HLA-lacking hematopoietic stem progenitor cells in aplastic anemia.干扰素-γ介导的再生障碍性贫血中造血的选择性抑制及缺乏人类白细胞抗原的造血干祖细胞的克隆优势
Leukemia. 2025 Apr 11. doi: 10.1038/s41375-025-02595-6.
2
Recurrent disease after a matched sibling hematopoietic transplant in an aplastic anemia patient with a disease risk allele, HLA-B*40:02.一名患有疾病风险等位基因HLA - B*40:02的再生障碍性贫血患者在接受匹配同胞造血干细胞移植后出现复发性疾病。
Blood Transfus. 2024 Nov;22(6):525-528. doi: 10.2450/BloodTransfus.674. Epub 2024 Aug 26.
3
Diagnosis of immune pathophysiology in patients with bone marrow failure.骨髓衰竭患者免疫病理生理学的诊断。
Int J Hematol. 2024 Mar;119(3):231-239. doi: 10.1007/s12185-022-03519-1. Epub 2023 Jan 7.
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Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities.不同种族再生障碍性贫血患者 HLA Ⅰ类等位基因的致病性和影响。
JCI Insight. 2022 Nov 22;7(22):e163040. doi: 10.1172/jci.insight.163040.
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Hematopoietic stem progenitor cells with malignancy-related gene mutations in patients with acquired aplastic anemia are characterized by the increased expression of CXCR4.获得性再生障碍性贫血患者中具有恶性肿瘤相关基因突变的造血干祖细胞的特征是CXCR4表达增加。
EJHaem. 2022 Jul 3;3(3):669-680. doi: 10.1002/jha2.515. eCollection 2022 Aug.
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Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia.抗环氧化酶 2 自身抗体是免疫性再生障碍性贫血的一种新型生物标志物。
Leukemia. 2022 Sep;36(9):2317-2327. doi: 10.1038/s41375-022-01654-6. Epub 2022 Aug 5.
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Current research status of HLA in immune-related diseases.免疫相关性疾病中 HLA 的研究现状。
Immun Inflamm Dis. 2021 Jun;9(2):340-350. doi: 10.1002/iid3.416. Epub 2021 Mar 3.
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A frequent nonsense mutation in exon 1 across certain HLA-A and -B alleles in leukocytes of patients with acquired aplastic anemia.在获得性再生障碍性贫血患者白细胞中，某些 HLA-A 和 -B 等位基因的外显子 1 中经常出现无意义突变。
Haematologica. 2021 Jun 1;106(6):1581-1590. doi: 10.3324/haematol.2020.247809.
本文引用的文献
1
Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.iPSC 衍生的再生障碍性贫血造血干细胞的造血作用可逃避细胞毒性 T 细胞的攻击。
Blood Adv. 2018 Feb 27;2(4):390-400. doi: 10.1182/bloodadvances.2017013342.
2
Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia.鉴定与获得性再生障碍性贫血自身抗原呈递密切相关的 HLA I 类等位基因。
Blood. 2017 May 25;129(21):2908-2916. doi: 10.1182/blood-2016-11-752378. Epub 2017 Feb 23.
3
Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia.获得性再生障碍性贫血患者中缺乏HLA - A等位基因表达的白细胞的临床意义及来源
Exp Hematol. 2016 Oct;44(10):931-939.e3. doi: 10.1016/j.exphem.2016.05.013. Epub 2016 May 29.
4
Clonal hematopoiesis in acquired aplastic anemia.获得性再生障碍性贫血中的克隆性造血
Blood. 2016 Jul 21;128(3):337-47. doi: 10.1182/blood-2016-01-636381. Epub 2016 Apr 27.
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Clonal evolution and clinical significance of copy number neutral loss of heterozygosity of chromosome arm 6p in acquired aplastic anemia.获得性再生障碍性贫血中6号染色体短臂拷贝数中性杂合性缺失的克隆进化及临床意义
Cancer Genet. 2016 Jan-Feb;209(1-2):1-10. doi: 10.1016/j.cancergen.2015.10.002. Epub 2015 Oct 30.
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Determination of HLA-A, -C, -B, -DRB1 allele and haplotype frequency in Japanese population based on family study.基于家系研究确定日本人群中HLA - A、- C、- B、- DRB1等位基因及单倍型频率
Tissue Antigens. 2015 Apr;85(4):252-9. doi: 10.1111/tan.12536. Epub 2015 Feb 27.
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Concise review: androgen receptor differential roles in stem/progenitor cells including prostate, embryonic, stromal, and hematopoietic lineages.简明综述：雄激素受体在包括前列腺、胚胎、基质和造血谱系在内的干细胞/祖细胞中的不同作用。
Stem Cells. 2014 Sep;32(9):2299-308. doi: 10.1002/stem.1722.
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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.急性白血病中白血病前造血干细胞的鉴定。
Nature. 2014 Feb 20;506(7488):328-33. doi: 10.1038/nature13038. Epub 2014 Feb 12.
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The androgen receptor: a biologically relevant vaccine target for the treatment of prostate cancer.雄激素受体：治疗前列腺癌的具有生物学相关性的疫苗靶标。
Cancer Immunol Immunother. 2013 Mar;62(3):585-96. doi: 10.1007/s00262-012-1363-9. Epub 2012 Oct 30.
10
Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia.获得性再生障碍性贫血中与拷贝数中性 6pLOH 相关的 HLA 等位基因频繁缺失。
Blood. 2011 Dec 15;118(25):6601-9. doi: 10.1182/blood-2011-07-365189. Epub 2011 Sep 30.
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