Department of Orthopedic Surgery, Sungmin Hospital, Incheon, 22789, South Korea.
Department of Orthopedic Surgery, Seouldaejung Hospital, Cheonan, 31156, South Korea.
Sci Rep. 2019 Mar 19;9(1):4871. doi: 10.1038/s41598-019-41152-x.
This study aimed to evaluate the incidence rates of and risk factors for complex regional pain syndrome type 1 (CRPS-1) after surgery for distal radius fractures (DRFs). Using data from January 2007 to December 2014, we analysed the data from the Korean Health Insurance Review and Assessment (HIRA) service. After extracting the data of patients aged ≥18 years whose diagnostic and operation codes for DRFs were entered into the HIRA database, we analysed the incidence rates of and risk factors for CRPS-1. From 2007 to 2014, 172,194 DRFs were treated surgically. Within 1 year postoperatively, 1,103 CRPS-1 cases were diagnosed, with an incidence of 0.64%. On univariate and multivariate analyses, the risk factors that significantly correlated with the incidence of CRPS-1 included female sex, rheumatoid arthritis, open reduction, open fracture, and accompanying ulnar fracture, whereas old age, psychiatric disease, and external fixation were not statistically significant. The incidence of CRPS-1 after surgery for DRF was very low (0.64%) in South Korea. Careful monitoring is necessary for patients with complex fractures and rheumatoid arthritis who are at increased risk of developing CRPS-1.
本研究旨在评估桡骨远端骨折（DRF）手术后 1 型复杂性区域疼痛综合征（CRPS-1）的发生率和风险因素。我们使用了 2007 年 1 月至 2014 年 12 月的数据，对韩国健康保险审查和评估（HIRA）服务的数据进行了分析。在提取了年龄≥18 岁的患者数据后，这些患者的 DRF 诊断和手术代码被输入 HIRA 数据库，我们分析了 CRPS-1 的发生率和风险因素。在 2007 年至 2014 年间，有 172194 例 DRF 接受了手术治疗。术后 1 年内，共诊断出 1103 例 CRPS-1，发生率为 0.64%。单因素和多因素分析显示，与 CRPS-1 发生率显著相关的风险因素包括女性、类风湿关节炎、切开复位、开放性骨折和伴发尺骨骨折，而年龄较大、精神疾病和外固定则无统计学意义。韩国 DRF 手术后 CRPS-1 的发生率非常低（0.64%）。对于复杂骨折和类风湿关节炎患者，应密切监测其发生 CRPS-1 的风险。
