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脑肿瘤患者抗癫痫治疗药物的选择

Choice of therapeutic anti-seizure medication in patients with brain tumour.

作者信息

Laghari Altaf Ali, Ahmed Syed Ijlal, Qadeer Namra, Shamim Muhammad Shahzad

机构信息

Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi. Pakistan.

出版信息

J Pak Med Assoc. 2019 Mar;69(3):442-444.

PMID:30890845
Abstract

Seizures are common in patients with brain tumours, even though prophylactic anti-seizure treatment for all patients with brain tumours is not recommended. Newer anti-epileptic drugs have shown benefits that outweigh the side effects of treatment and can also be given in combination with traditional anti-epileptic drugs. The authors have reviewed the literature on the various combinations of anti-epileptics in patients with seizures and brain tumours.

摘要

癫痫发作在脑肿瘤患者中很常见,尽管不建议对所有脑肿瘤患者进行预防性抗癫痫治疗。新型抗癫痫药物已显示出其益处大于治疗副作用,并且也可与传统抗癫痫药物联合使用。作者回顾了关于癫痫发作合并脑肿瘤患者使用各种抗癫痫药物组合的文献。

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1
Choice of therapeutic anti-seizure medication in patients with brain tumour.脑肿瘤患者抗癫痫治疗药物的选择
J Pak Med Assoc. 2019 Mar;69(3):442-444.
2
Efficacy of anti-epileptic drugs in patients with gliomas and seizures.抗癫痫药物对胶质瘤伴癫痫患者的疗效。
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Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management.脑肿瘤患者的癫痫:流行病学、机制与管理
Lancet Neurol. 2007 May;6(5):421-30. doi: 10.1016/S1474-4422(07)70103-5.
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Seizures and Anticonvulsants in Brain Tumours: Frequency, Mechanisms and Anti-Epileptic Management.脑肿瘤中的癫痫发作和抗癫痫药物:频率、机制和抗癫痫药物管理。
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Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.抗癫痫药物和叶酸在孕期的使用、癫痫发作和畸形结局:喀拉拉邦癫痫与妊娠注册研究 20 多年的变化。
Epilepsy Res. 2020 Jan;159:106250. doi: 10.1016/j.eplepsyres.2019.106250. Epub 2019 Dec 9.
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Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.低剂量吡仑帕奈添加治疗左乙拉西坦无法控制癫痫的胶质瘤患者的经验
Neurol Med Chir (Tokyo). 2020 Jan 15;60(1):37-44. doi: 10.2176/nmc.oa.2018-0245. Epub 2019 Nov 21.
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Seizures in low- and high-grade gliomas: current management and future outlook.低级别和高级别胶质瘤中的癫痫发作:当前的治疗管理和未来展望。
Expert Rev Anticancer Ther. 2010 May;10(5):663-9. doi: 10.1586/era.10.48.
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The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.癫痫与线粒体自噬和自噬相关痴呆(MAD)受损之间的相互作用:治疗方法综述
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[Glioma-associated epilepsy].[胶质瘤相关性癫痫]
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[Anticonvulsant therapy for brain tumour-related epilepsy].[脑肿瘤相关性癫痫的抗惊厥治疗]
Fortschr Neurol Psychiatr. 2014 Dec;82(12):678-90. doi: 10.1055/s-0034-1385475. Epub 2014 Dec 9.

引用本文的文献

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Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy.胶质母细胞瘤和肿瘤相关性癫痫中的谷氨酸能机制。
Cells. 2021 May 17;10(5):1226. doi: 10.3390/cells10051226.
2
Antiepileptic Drugs in the Management of Cerebral Metastases.抗癫痫药物在脑转移瘤治疗中的应用。
Neurosurg Clin N Am. 2020 Oct;31(4):589-601. doi: 10.1016/j.nec.2020.06.008.