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脊柱结核诊断与管理中的挑战:病例系列

Challenges in the Diagnosis and Management of Spinal Tuberculosis: Case Series.

作者信息

Dean Anudariya, Zyck Stephanie, Toshkezi Gentian, Galgano Michael, Marawar Satya

机构信息

Neurosurgery, State University of New York Upstate Medical University, Syracuse, USA.

Neurosurgery, Thomas Jefferson University Hospitals, Philadelphia, USA.

出版信息

Cureus. 2019 Jan 8;11(1):e3855. doi: 10.7759/cureus.3855.

DOI:10.7759/cureus.3855
PMID:30891395
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6411342/
Abstract

Though uncommon in developed countries, spinal tuberculosis must still be considered in patients with a suspicious clinical history, to avoid delays in treatment. This case series highlights the special considerations that need to be taken into account while tackling the diagnostic and therapeutic challenges associated with this disease. We present two interesting cases of spinal tuberculosis. The first case was a 26-year-old female who presented with chronic back pain and an initial misdiagnosis of ankylosing spondylitis. The second case was a 26-year-old male with new lower extremity weakness, numbness, and urinary retention. Both cases had clear indications for surgery, however, the first case was treated with medical management upon patient request. The patient was managed non-surgically and improved clinically though she may need surgery in the future. The second case was treated with emergency surgery and the patient regained full neurologic function at follow-up. These cases demonstrate the importance of considering spinal tuberculosis in the differential diagnosis of high-risk patients as well as individualizing treatment strategies for each patient.

摘要

虽然在发达国家脊柱结核并不常见,但对于有可疑临床病史的患者仍必须考虑到该病,以避免治疗延误。本病例系列突出了在应对与该疾病相关的诊断和治疗挑战时需要考虑的特殊因素。我们呈现两例有趣的脊柱结核病例。第一例是一名26岁女性,表现为慢性背痛,最初被误诊为强直性脊柱炎。第二例是一名26岁男性,出现新的下肢无力、麻木和尿潴留。两例均有明确的手术指征,然而,第一例根据患者要求接受了药物治疗。该患者接受了非手术治疗,临床症状有所改善,不过未来可能仍需手术。第二例接受了急诊手术,随访时患者神经功能完全恢复。这些病例表明,在高危患者的鉴别诊断中考虑脊柱结核以及为每位患者制定个体化治疗策略的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/4cedf9c1d6da/cureus-0011-00000003855-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/5a7305e8d236/cureus-0011-00000003855-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/abc927b07945/cureus-0011-00000003855-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/ce3bad3026b4/cureus-0011-00000003855-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/f9357a799a8b/cureus-0011-00000003855-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/998bd4609467/cureus-0011-00000003855-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/7a1becd0240c/cureus-0011-00000003855-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/416a5d7a3f98/cureus-0011-00000003855-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/4cedf9c1d6da/cureus-0011-00000003855-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/5a7305e8d236/cureus-0011-00000003855-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/abc927b07945/cureus-0011-00000003855-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/ce3bad3026b4/cureus-0011-00000003855-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/f9357a799a8b/cureus-0011-00000003855-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/998bd4609467/cureus-0011-00000003855-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/7a1becd0240c/cureus-0011-00000003855-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/416a5d7a3f98/cureus-0011-00000003855-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/6411342/4cedf9c1d6da/cureus-0011-00000003855-i08.jpg

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本文引用的文献

1
Spinal tuberculosis: a review.脊柱结核:综述
J Spinal Cord Med. 2011;34(5):440-54. doi: 10.1179/2045772311Y.0000000023.
2
A new classification and guide for surgical treatment of spinal tuberculosis.脊柱结核外科治疗的新分类与指南
Int Orthop. 2008 Feb;32(1):127-33. doi: 10.1007/s00264-006-0278-5. Epub 2007 Jan 6.
3
Routine surgery in addition to chemotherapy for treating spinal tuberculosis.除化疗外,采用常规手术治疗脊柱结核。
Cochrane Database Syst Rev. 2006 Jan 25;2006(1):CD004532. doi: 10.1002/14651858.CD004532.pub2.
4
The natural history of post-tubercular kyphosis in children. Radiological signs which predict late increase in deformity.儿童结核后凸畸形的自然史。预测畸形后期加重的放射学征象。
J Bone Joint Surg Br. 2001 Sep;83(7):954-62. doi: 10.1302/0301-620x.83b7.12170.
5
Tuberculosis of the thoracic spine. A classification based on the selection of surgical strategies.胸椎结核。基于手术策略选择的分类。
J Bone Joint Surg Br. 2001 Aug;83(6):859-63. doi: 10.1302/0301-620x.83b6.11142.
6
Short-course chemotherapy for tuberculosis of the spine. A comparison between ambulant treatment and radical surgery--ten-year report.脊柱结核的短程化疗。门诊治疗与根治性手术的比较——十年报告。
J Bone Joint Surg Br. 1999 May;81(3):464-71. doi: 10.1302/0301-620x.81b3.9043.
7
A clinical study and classification of posterior spinal tuberculosis.
Int Orthop. 1985;9(3):147-52. doi: 10.1007/BF00268164.
8
Five-year assessments of controlled trials of ambulatory treatment, debridement and anterior spinal fusion in the management of tuberculosis of the spine. Studies in Bulawayo (Rhodesia) and in Hong Kong. Sixth report of the Medical Research Council Working Party on Tuberculosis of the Spine.脊柱结核治疗中门诊治疗、清创术和前路脊柱融合术对照试验的五年评估。在布拉瓦约(罗德西亚)和香港开展的研究。医学研究委员会脊柱结核工作小组第六次报告。
J Bone Joint Surg Br. 1978 May;60-B(2):163-77. doi: 10.1302/0301-620X.60B2.350883.