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镰状细胞病与下肢关节置换术后再入院率:2007-2014 年多州分析

Sickle cell disease and readmissions rates after lower extremity arthroplasty: a multistate analysis 2007-2014.

机构信息

Department of Anesthesiology, Weill Cornell Medicine, 525 East 68th Street, New York, NY 10065, USA.

Department of Anesthesiology, New York-Presbyterian Hospital/Weill Cornell Medicine, 525 East 68th Street, New York, NY 10065, USA.

出版信息

J Comp Eff Res. 2019 Apr;8(6):403-422. doi: 10.2217/cer-2018-0098. Epub 2019 Mar 20.

DOI:10.2217/cer-2018-0098
PMID:30892071
Abstract

AIM

To compare readmission rates between patients with sickle cell disease (SCD) and non-sickle cell disease undergoing total hip and knee arthroplasty (THA and TKA).

METHODS

Identified adult patients who underwent THA or TKA from 2007 to 2014 in California, Florida, New York, Maryland and Kentucky using a multistate database. Outcomes were 30- and 90-day readmission rates, mortality, complications, length of stay and hospital charges. Logistic regression models were used for analysis.

RESULTS

Compared with non-sickle cell disease patients following TKA and THA, SCD patients had higher odds of 30- (odds ratio [OR]: 3.79) and 90-day readmissions (OR: 4.15), mortality (OR: 6.54), more complications, longer length of stay, and higher total charges.

CONCLUSION

Following TKA and THA, SCD is associated with higher readmissions and worse outcomes.

摘要

目的

比较镰状细胞病(SCD)患者和非镰状细胞病患者在全髋关节置换术(THA)和全膝关节置换术(TKA)后的再入院率。

方法

使用多州数据库,确定 2007 年至 2014 年期间在加利福尼亚州、佛罗里达州、纽约州、马里兰州和肯塔基州接受 THA 或 TKA 的成年患者。结果为 30 天和 90 天的再入院率、死亡率、并发症、住院时间和住院费用。使用逻辑回归模型进行分析。

结果

与 TKA 和 THA 后非镰状细胞病患者相比,SCD 患者的 30 天(优势比 [OR]:3.79)和 90 天再入院(OR:4.15)、死亡率(OR:6.54)、更多并发症、更长的住院时间和更高的总费用的可能性更高。

结论

在接受 TKA 和 THA 后,SCD 与更高的再入院率和更差的结局相关。

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引用本文的文献

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J Clin Med. 2024 Jul 15;13(14):4129. doi: 10.3390/jcm13144129.
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Is cost of surgery and hospital length of stay increased for sickle cell disease patients undergoing total joint replacement surgeries? Systematic review and multivariate meta-analysis.镰状细胞病患者接受全关节置换手术时,手术费用和住院时间会增加吗?系统评价和多变量荟萃分析。
J Orthop. 2023 Dec 14;50:116-121. doi: 10.1016/j.jor.2023.12.002. eCollection 2024 Apr.
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How does sickle cell disease affect the peri-operative outcome in patients undergoing total knee arthroplasty? A large-scale, National Inpatient Sample-based study.
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Arch Orthop Trauma Surg. 2023 Aug;143(8):5261-5268. doi: 10.1007/s00402-022-04762-1. Epub 2023 Jan 2.
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Machine-learning algorithms for predicting hospital re-admissions in sickle cell disease.机器学习算法在镰状细胞病患者再入院预测中的应用。
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