镰状细胞病与下肢关节置换术后再入院率：2007-2014 年多州分析
Sickle cell disease and readmissions rates after lower extremity arthroplasty: a multistate analysis 2007-2014.
机构信息
Department of Anesthesiology, Weill Cornell Medicine, 525 East 68th Street, New York, NY 10065, USA.
Department of Anesthesiology, New York-Presbyterian Hospital/Weill Cornell Medicine, 525 East 68th Street, New York, NY 10065, USA.
出版信息
J Comp Eff Res. 2019 Apr;8(6):403-422. doi: 10.2217/cer-2018-0098. Epub 2019 Mar 20.
AIM
To compare readmission rates between patients with sickle cell disease (SCD) and non-sickle cell disease undergoing total hip and knee arthroplasty (THA and TKA).
METHODS
Identified adult patients who underwent THA or TKA from 2007 to 2014 in California, Florida, New York, Maryland and Kentucky using a multistate database. Outcomes were 30- and 90-day readmission rates, mortality, complications, length of stay and hospital charges. Logistic regression models were used for analysis.
RESULTS
Compared with non-sickle cell disease patients following TKA and THA, SCD patients had higher odds of 30- (odds ratio [OR]: 3.79) and 90-day readmissions (OR: 4.15), mortality (OR: 6.54), more complications, longer length of stay, and higher total charges.
CONCLUSION
Following TKA and THA, SCD is associated with higher readmissions and worse outcomes.
目的
比较镰状细胞病（SCD）患者和非镰状细胞病患者在全髋关节置换术（THA）和全膝关节置换术（TKA）后的再入院率。
方法
使用多州数据库，确定 2007 年至 2014 年期间在加利福尼亚州、佛罗里达州、纽约州、马里兰州和肯塔基州接受 THA 或 TKA 的成年患者。结果为 30 天和 90 天的再入院率、死亡率、并发症、住院时间和住院费用。使用逻辑回归模型进行分析。
结果
与 TKA 和 THA 后非镰状细胞病患者相比，SCD 患者的 30 天（优势比 [OR]：3.79）和 90 天再入院（OR：4.15）、死亡率（OR：6.54）、更多并发症、更长的住院时间和更高的总费用的可能性更高。
结论
在接受 TKA 和 THA 后，SCD 与更高的再入院率和更差的结局相关。
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