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机械通气患者支气管卫生技术的比较:一项随机临床试验。

Comparison of bronchial hygiene techniques in mechanically ventilated patients: a randomized clinical trial.

作者信息

Naue Wagner da Silva, Herve Bruno Barcelos, Vieira Fernando Nataniel, Deponti Gracieli Nadalon, Martins Luciane de Fraga, Dias Alexandre Simões, Vieira Silvia Regina Rios

机构信息

Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul - Porto Alegre (RS), Brasil.

出版信息

Rev Bras Ter Intensiva. 2019;31(1):39-46. doi: 10.5935/0103-507X.20190005. Epub 2019 Mar 14.

Abstract

OBJECTIVE

To compare the effects of vibrocompression and hyperinflation with mechanical ventilator techniques alone and in combination (hyperinflation with mechanical ventilator + vibrocompression) on the amount of aspirated secretion and the change in hemodynamic and pulmonary parameters.

METHODS

A randomized clinical trial with critically ill patients on mechanical ventilation conducted in the intensive care unit of a university hospital. The patients were randomly allocated to receive one of the bronchial hygiene techniques for 10 minutes (vibrocompression or hyperinflation with mechanical ventilator or hyperinflation with mechanical ventilator + vibrocompression). Afterwards, the patients were again randomly allocated to receive either the previous randomly allocated technique or only tracheal aspiration. The weight of aspirated secretions (in grams), ventilatory mechanics and cardiopulmonary data before and after the application of the techniques were analyzed. The tracheal reintubation frequency and time and mortality on mechanical ventilation were also evaluated.

RESULTS

A total of 93 patients (29 vibrocompression, 32 hyperinflation with mechanical ventilator and 32 hyperinflation with mechanical ventilator + vibrocompression) on mechanical ventilation for more than 24 hours were included. The hyperinflation with mechanical ventilator + vibrocompression group was the only one that presented a significant increase in aspirated secretions compared to tracheal aspiration alone [0.7g (0.1 - 2.5g) versus 0.2g (0.0 - 0.6g), p value = 0.006].

CONCLUSION

Compared to tracheal aspiration alone, the combination of hyperinflation with mechanical ventilator + vibrocompression techniques was most efficient for increasing the amount of aspirated secretions.

摘要

目的

比较振动排痰、单纯机械通气技术的肺过度充气以及两者联合应用(机械通气肺过度充气+振动排痰)对吸出分泌物量以及血流动力学和肺部参数变化的影响。

方法

在一所大学医院的重症监护病房对接受机械通气的重症患者进行一项随机临床试验。将患者随机分配接受其中一种支气管清洁技术10分钟(振动排痰、机械通气肺过度充气或机械通气肺过度充气+振动排痰)。之后,再次将患者随机分配接受之前随机分配的技术或仅进行气管抽吸。分析应用技术前后吸出分泌物的重量(克)、通气力学和心肺数据。还评估了气管再插管频率和时间以及机械通气期间的死亡率。

结果

共纳入93例机械通气超过24小时的患者(29例接受振动排痰,32例接受机械通气肺过度充气,32例接受机械通气肺过度充气+振动排痰)。与单纯气管抽吸相比,机械通气肺过度充气+振动排痰组是唯一吸出分泌物显著增加的组[0.7克(0.1 - 2.5克)对0.2克(0.0 - 0.6克),p值=0.006]。

结论

与单纯气管抽吸相比,机械通气肺过度充气+振动排痰技术联合应用在增加吸出分泌物量方面最有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1881/6443316/c70f13990b58/rbti-31-01-0039-g01.jpg

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