Laboratory of Biorheology and Medical Ultrasonics, University of Montreal Hospital Research Center (CRCHUM), Montreal, Quebec, Canada.
Phys Med Biol. 2019 May 2;64(9):095025. doi: 10.1088/1361-6560/ab1145.
As the complexity of ultrasound signal processing algorithms increases, it becomes more difficult to demonstrate their added value and thus robust validation strategies are required. We propose a method of manufacturing ultrasonic vascular phantoms mimicking an atheromatous plaque in an internal carotid artery bifurcation for applications in flow imaging and elastography. During the fabrication process, a soft inclusion mimicking a stenotic lipid pool was embedded within the vascular wall. Mechanical testing measured Young's moduli of the vascular wall and soft inclusion at 342 ± 25 kPa and 17 ± 3 kPa, respectively. B-mode, color Doppler, power Doppler, shear wave elastography, and strain elastography images of the different phantoms were produced to show the validity of the fabrication process. Because of their realistic geometries and mechanical properties, those phantoms may become advantageous for fluid-structure experimental modeling and validation of new ultrasound-based imaging technologies.
随着超声信号处理算法的复杂性增加，展示其附加值变得更加困难，因此需要稳健的验证策略。我们提出了一种制造模拟颈内动脉分叉处动脉粥样硬化斑块的超声血管模型的方法，用于血流成像和弹性成像应用。在制造过程中，将一个模拟狭窄脂质池的软嵌体嵌入血管壁内。力学测试测量血管壁和软嵌体的杨氏模量分别为 342 ± 25 kPa 和 17 ± 3 kPa。制作了不同模型的 B 模式、彩色多谱勒、能量多谱勒、剪切波弹性成像和应变弹性成像图像，以显示制造过程的有效性。由于其真实的几何形状和力学性能，这些模型可能成为流体结构实验建模和新的基于超声的成像技术验证的有利工具。
