Clinical and Biological Psychology, University of Trier, Trier, Germany,
Clinical and Biological Psychology, University of Trier, Trier, Germany.
Neuropsychobiology. 2019;78(1):27-30. doi: 10.1159/000498866. Epub 2019 Mar 20.
BACKGROUND/AIMS: Restrained eating has been linked to binge eating under disinhibited circumstances and is therefore considered a risk factor to develop clinical eating disorders such as bulimia nervosa or binge eating disorder. The present study investigated the release of gastrointestinal peptides such as ghrelin and PYY after stress, as well as cortisol in young females classified as restrained and unrestrained eaters.
The study was done in the laboratory of the Department for Biological and Clinical Psychology at the University of Trier. The sample consisted of 48 females, and the stressor was the Trier Social Stress Test. Blood samples for peptides and salivary cortisol were taken.
Higher ghrelin, but lower cortisol after stress was obtained for restrained eaters; no stress-related changes for PYY were observed.
Restrained eaters suffer from a possible stress-related biological dysregulation of eating, posing them at risk for eating and weight disorders.
背景/目的：在不受抑制的情况下，节食与暴食有关，因此被认为是发展神经性贪食症或暴食障碍等临床进食障碍的风险因素。本研究调查了应激后胃肠肽（如 ghrelin 和 PYY）以及皮质醇的释放情况，这些女性被分为节食者和非节食者。
该研究在特里尔大学生物与临床心理学系的实验室进行。样本由 48 名女性组成，应激源是特里尔社会应激测试。采集肽和唾液皮质醇的血液样本。
节食者在应激后表现出较高的 ghrelin，但皮质醇较低；PYY 没有观察到与应激相关的变化。
节食者可能存在与应激相关的进食生物调节紊乱，使他们面临进食和体重障碍的风险。
