Radiology, The Nippon Dental University Niigata Hospital, Niigata, Japan.
Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.
Dentomaxillofac Radiol. 2019 Sep;48(6):20180454. doi: 10.1259/dmfr.20180454. Epub 2019 Apr 24.
To evaluate shear wave elastography in differentiating between benign and malignant cervical lymph nodes in patients with oral carcinoma.
77 patients with oral squamous cell carcinoma were examined by B-mode and shear wave elastography with a 14 MHz linear transducer. The integrated shear wave elastography software allowed the operator to place regions of interest of various sizes within the elastography window, and automatically displayed shear elastic modulus data (kPa) for each region of interest. The relationship between size and shear elastic modulus of cervical lymph nodes was assessed by Pearson's rank correlation test. The shear elastic modulus of cervical lymph nodes in benign and malignant were evaluated using the Mann-Whitney test. The analyses were used with a 5% significance level.
We plotted shear elastic modulus (X) against minimal axial diameter of cervical lymph nodes (Y), and observed a significant correlation [ = 0.091 X + 4.648 (R = 0.603, = 0.000, = 77)]. Furthermore, the shear elastic modulus of the malignant cervical lymph nodes (105.9 ± 5.2 kPa) was higher than that of benign (11.9 ± 4.4 kPa, = 0.000).
The shear wave elastography is an effective technique for the objectively and quantitatively diagnosis of cervical lymph node metastases of the oral carcinoma.
评估剪切波弹性成像在鉴别口腔癌患者良恶性颈淋巴结中的作用。
采用 14MHz 线性探头对 77 例口腔鳞状细胞癌患者进行 B 型及剪切波弹性成像检查。整合的剪切波弹性成像软件允许操作者在弹性成像窗口内放置不同大小的感兴趣区，并自动显示每个感兴趣区的剪切弹性模量数据（kPa）。采用 Pearson 秩相关检验评估颈淋巴结大小与剪切弹性模量之间的关系。采用 Mann-Whitney U 检验评估良恶性颈淋巴结的剪切弹性模量。采用 5%的显著性水平进行分析。
我们将剪切弹性模量（X）与颈淋巴结最小轴向直径（Y）作图，观察到显著相关性[ = 0.091 X + 4.648（R = 0.603， = 0.000， = 77）]。此外，恶性颈淋巴结的剪切弹性模量（105.9 ± 5.2 kPa）高于良性（11.9 ± 4.4 kPa， = 0.000）。
剪切波弹性成像技术是一种客观、定量诊断口腔癌颈淋巴结转移的有效方法。
