Suh Chong Hyun, Choi Young Jun, Baek Jung Hwan, Lee Jeong Hyun
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul, 138-736, Republic of Korea.
Department of Radiology, Namwon Medical Center, 365, Chungjeong-Ro, Namwon-Si, Jeollabuk-Do, 590-702, Republic of Korea.
Eur Radiol. 2017 Jan;27(1):222-230. doi: 10.1007/s00330-016-4378-3. Epub 2016 May 5.
To evaluate the diagnostic performance of shear wave elastography for malignant cervical lymph nodes.
We searched the Ovid-MEDLINE and EMBASE databases for published studies regarding the use of shear wave elastography for diagnosing malignant cervical lymph nodes. The diagnostic performance of shear wave elastography was assessed using bivariate modelling and hierarchical summary receiver operating characteristic modelling. Meta-regression analysis and subgroup analysis according to acoustic radiation force impulse imaging (ARFI) and Supersonic shear imaging (SSI) were also performed.
Eight eligible studies which included a total sample size of 481 patients with 647 cervical lymph nodes, were included. Shear wave elastography showed a summary sensitivity of 81 % (95 % CI: 72-88 %) and specificity of 85 % (95 % CI: 70-93 %). The results of meta-regression analysis revealed that the prevalence of malignant lymph nodes was a significant factor affecting study heterogeneity (p < .01). According to the subgroup analysis, the summary estimates of the sensitivity and specificity did not differ between ARFI and SSI (p = .93).
Shear wave elastography is an acceptable imaging modality for diagnosing malignant cervical lymph nodes. We believe that both ARFI and SSI may have a complementary role for diagnosing malignant cervical lymph nodes.
• Shear wave elastography is acceptable modality for diagnosing malignant cervical lymph nodes. • Shear wave elastography demonstrated summary sensitivity of 81 % and specificity of 85 %. • ARFI and SSI have complementary roles for diagnosing malignant cervical lymph nodes.
评估剪切波弹性成像对颈部恶性淋巴结的诊断性能。
我们在Ovid-MEDLINE和EMBASE数据库中检索已发表的关于使用剪切波弹性成像诊断颈部恶性淋巴结的研究。使用双变量建模和分层汇总接收器操作特征建模评估剪切波弹性成像的诊断性能。还根据声辐射力脉冲成像（ARFI）和超声剪切波成像（SSI）进行了Meta回归分析和亚组分析。
纳入了8项符合条件的研究，总样本量为481例患者，共647个颈部淋巴结。剪切波弹性成像的汇总敏感性为81%（95%CI：72-88%），特异性为85%（95%CI：70-93%）。Meta回归分析结果显示，恶性淋巴结的患病率是影响研究异质性的一个重要因素（p < 0.01）。根据亚组分析，ARFI和SSI之间的敏感性和特异性汇总估计值没有差异（p = 0.93）。
剪切波弹性成像是诊断颈部恶性淋巴结的一种可接受的成像方式。我们认为ARFI和SSI在诊断颈部恶性淋巴结方面可能具有互补作用。
• 剪切波弹性成像是诊断颈部恶性淋巴结的可接受方式。• 剪切波弹性成像的汇总敏感性为81%，特异性为85%。• ARFI和SSI在诊断颈部恶性淋巴结方面具有互补作用。
