Department of Neurosciences, Deutsches Hospital, Buenos Aires, Argentine Republic.
Rheumatology Unit, Deutsches Hospital, Buenos Aires, Argentine Republic.
CNS Spectr. 2019 Dec;24(6):605-608. doi: 10.1017/S1092852918001608.
Fibromyalgia (FM) is a chronic pain syndrome with a controversial etiopathogenesis. Patients with FM usually complain of cognitive symptoms, which are described as "fibrofog." These cognitive complaints might be caused partially by dissociative disorders (DD). The aim of this research is to determine the association between FM and DD.
The authors conducted a case-control study for this purpose, integrated by 3 groups: control (C), patients with rheumatic disorders (R), and patients with FM (FM), who were compared through the Dissociative Experiences Scale (DES).The findings are as follows: 42% were taking medications in the FM group, and their differences in scores with those who were not under medications were then considered. In terms of the results, the FM group showed higher scores than both C and R groups (p < 0.05). Patients with FM who were taking antidepressants had lower scores than those who were not (Z-score -8.03; p < 0.05); and finally, 5.71% had a score over 30 (χ2 = 3.73, p = 0.15).
Patients with FM had higher scores, which might be related to the association of dissociative experiences, lifetime trauma, and victimization. Antidepressants might have some role on dissociative symptoms as well.
纤维肌痛（FM）是一种慢性疼痛综合征，其发病机制存在争议。FM 患者通常会出现认知症状，这些症状被描述为“fibrofog”。这些认知症状可能部分是由分离障碍（DD）引起的。本研究旨在确定 FM 与 DD 之间的关联。
作者为此进行了一项病例对照研究，包括 3 组：对照组（C）、风湿性疾病患者组（R）和纤维肌痛患者组（FM），通过分离体验量表（DES）对这些组进行比较。结果如下：FM 组有 42%的患者正在服用药物，然后考虑了他们与未服用药物的患者在分数上的差异。结果显示，FM 组的得分高于 C 组和 R 组（p<0.05）。服用抗抑郁药的 FM 患者的得分低于未服用的患者（Z 分数-8.03；p<0.05）；最后，有 5.71%的患者得分超过 30（χ2=3.73，p=0.15）。
FM 患者的得分较高，这可能与分离体验、终生创伤和受害有关。抗抑郁药也可能对分离症状有一定的作用。
