加拿大的生长激素疗法：一个时代的结束与另一个时代的开始。
Growth hormone therapy in Canada: end of one era and beginning of another.
作者信息
Dean H J, Friesen H G
出版信息
CMAJ. 1986 Aug 15;135(4):297-301.
Abstract
This paper reviews the difficulties in diagnosing a true deficiency of growth hormone (GH), the long-term results of therapy, the Canadian experience in treating GH deficiency, including the contributions made by the Medical Research Council's Therapeutic Trial of Human Growth Hormone, and the occurrence of Creutzfeldt-Jakob disease in recipients of GH therapy. It also speculates on potential alternatives to treatment with GH derived from human pituitaries.
摘要
本文回顾了诊断生长激素（GH）真正缺乏的困难、治疗的长期结果、加拿大治疗GH缺乏的经验，包括医学研究委员会人类生长激素治疗试验所做的贡献，以及接受GH治疗者发生克雅氏病的情况。它还推测了源自人垂体的GH治疗的潜在替代方法。
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引用本文的文献
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Creutzfeldt-Jakob disease: the Canadian situation.
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The epidemiology of Creutzfeldt-Jakob disease in Canada: a review of mortality data.
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