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溺水兔模型肺CT图像参数的特征性变化及三维虚拟测量

Characteristic Changes and 3D Virtual Measurement of Lung CT Image Parameters in the Drowning Rabbit Model.

作者信息

Jian J Q, Deng D Y, Wan L, Zou D H, Wang Z Q, Liu N G, Chen Y J

机构信息

Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, Jiangsu Province, China.

Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.

出版信息

Fa Yi Xue Za Zhi. 2019 Feb;35(1):1-4. doi: 10.12116/j.issn.1004-5619.2019.01.001. Epub 2019 Feb 25.

DOI:10.12116/j.issn.1004-5619.2019.01.001
PMID:30896111
Abstract

OBJECTIVES

To use virtual anatomy technique in the analysis of post-mortem characteristic changes of CT images in the experimental drowning rabbit model and the related parameters in 3D virtual model, so as to explore its application value in the diagnosis of drowning in forensic pathology.

METHODS

A model of drowning rabbits was established, with animal models of hemorrhagic shock and mechanical asphyxia as the controls. CT scan was performed on the experimental animals, and the differences in imaging features between the groups were compared by morphological reading of the tomographic images. CT data were imported into Mimics 14.0 software for 3D modeling. The CT values and lung volumes were calculated by the software, and the differences on CT values and lung volumes brought by different causes of death were analyzed.

RESULTS

The CT images of lungs in the drowning group showed characteristic ground-glass opacity (diffuse and uniform density increase). There were no obvious abnormalities in hemorrhagic shock group, and only a few similar changes were found in the mechanical asphyxia group. Compared with the controls, the CT values and the lung volumes in the drowning group were significantly increased <0.05.

CONCLUSIONS

Based on post-mortem lung imaging, the combination of CT value and lung volume changes can effectively reflect the virtual anatomical features in drowning, and provide a diagnostic basis for the forensic identification of drowning.

摘要

目的

运用虚拟解剖技术分析实验性溺水兔模型CT图像的死后特征性变化及三维虚拟模型中的相关参数,以探讨其在法医学病理诊断溺死中的应用价值。

方法

建立溺水兔模型,以失血性休克和机械性窒息动物模型作为对照。对实验动物进行CT扫描,通过断层图像的形态学阅片比较各组成像特征的差异。将CT数据导入Mimics 14.0软件进行三维建模。利用该软件计算CT值和肺容积,并分析不同死因导致的CT值和肺容积差异。

结果

溺水组肺的CT图像显示出特征性磨玻璃样密度增高影(密度弥漫性均匀增加)。失血性休克组无明显异常,机械性窒息组仅发现少数类似改变。与对照组相比,溺水组的CT值和肺容积显著增加(P<0.05)。

结论

基于死后肺成像,CT值与肺容积变化相结合能够有效反映溺死的虚拟解剖特征,为溺死的法医学鉴定提供诊断依据。

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