Peng Zhiyong, Zhong Peiwen, Li Li, Wu Weibin, Xiao Cheng, Feng Chunlei, Du Weian, Chen Ling
a Institute of Nanfang-Chunfu Hematology of Children , Taixin hospital , Dongguan , PR China.
b Nanfang Hospital, Southern Medical University/The First School of Clinical Medicine, Southern Medical University , Guangzhou , PR China.
Ann Hum Biol. 2019 Mar;46(2):187-192. doi: 10.1080/03014460.2019.1595725. Epub 2019 Apr 17.
To investigate the genetic polymorphisms of 19 STR loci in the Teochew population of Chaozhou. Nineteen STR loci of 631 unrelated Teochew people in Chaozhou were detected by using the AGCU Expressmarker 20 kit. The allele frequency ranged from 0.0008-0.5577. The combined power of discrimination and combined probability of excluding paternity is over 0.999,999,999,999,999,999,999,999,999,999 and 0.999,999,992,549,546, respectively. The principal component analysis based on the 11 shared STR loci showed the Teochew population was most genetically related to the Fujian Han population. The results demonstrate the set of 19 autosomal STRs could provide robust genetics information for individual identification, paternity testing and human genetics research in the Teochew population.
为研究潮州潮汕人群中19个STR基因座的遗传多态性。采用AGCU Expressmarker 20试剂盒对潮州市631名无血缘关系的潮汕人进行19个STR基因座检测。等位基因频率范围为0.0008 - 0.5577。累积个体识别率和累积非父排除率分别超过0.999,999,999,999,999,999,999,999,999,999和0.999,999,992,549,546。基于11个共享STR基因座的主成分分析表明，潮汕人群与福建汉族人群的遗传关系最为密切。结果表明，这19个常染色体STR基因座可为潮汕人群的个体识别、亲子鉴定及人类遗传学研究提供可靠的遗传学信息。
