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先天性白内障手术的视觉效果及并发症

Visual outcomes and complications of congenital cataract surgery.

作者信息

Louison S, Blanc J, Pallot C, Alassane S, Praudel A, Bron A-M, Creuzot-Garcher C

机构信息

Department of ophthalmology, university hospital, 21000 Dijon, France.

Department of epidemiology, university hospital, 21000 Dijon, France.

出版信息

J Fr Ophtalmol. 2019 Apr;42(4):368-374. doi: 10.1016/j.jfo.2018.10.007. Epub 2019 Mar 18.

DOI:10.1016/j.jfo.2018.10.007
PMID:30898370
Abstract

PURPOSE

To describe the visual results and postoperative complications of congenital cataract surgeries performed between 2005 and 2016.

METHODS

A retrospective consecutive case series of congenital cataract surgeries was carried out at the Dijon University Hospital in France. Intraocular lens implantation was primary or secondary according to age. Pre- and post-operative assessment was performed through ophthalmologic consultations with orthoptic measurements. Visual function and adverse events were recorded.

RESULTS

Fifty-six consecutive procedures were evaluated in 37 infants. Overall, 26.8% of patients had unilateral cataracts, and 73.2% had bilateral cataracts. Median age at surgery was 1.0 years [IQR (interquartile range): 0.3-5.2] and 2.7 years [IQR: 0.4-9.5] for unilateral and bilateral cataracts, respectively. Median best-corrected visual acuity (BCVA) at the last follow-up was 0.5logMAR [IQR: 0.2-0.8] and 0.1logMAR [IQR: 0.0-0.8] for the unilateral and bilateral group, respectively. Posterior capsule opacification (PCO) was the primary postoperative complication: 60.0% in unilateral cataract and 46.3% in bilateral cataracts (P=0.019). Median follow-up was 2.0 years [IQR: 1.0-5.0].

CONCLUSION

Congenital cataract surgery appears to be safe and effective when combined with early, conscientious amblyopia treatment. Bilateral congenital cataracts had better visual outcome than unilateral cataract.

摘要

目的

描述2005年至2016年间进行的先天性白内障手术的视觉效果和术后并发症。

方法

在法国第戎大学医院开展了一项先天性白内障手术的回顾性连续病例系列研究。根据年龄进行一期或二期人工晶状体植入。通过眼科会诊及视光学测量进行术前和术后评估。记录视觉功能和不良事件。

结果

对37例婴儿的56例连续手术进行了评估。总体而言,26.8%的患者为单侧白内障,73.2%为双侧白内障。单侧和双侧白内障手术的中位年龄分别为1.0岁[四分位间距(IQR):0.3 - 5.2]和2.7岁[IQR:0.4 - 9.5]。末次随访时,单侧和双侧组的最佳矫正视力(BCVA)中位数分别为0.5logMAR[IQR:0.2 - 0.8]和0.1logMAR[IQR:0.0 - 0.8]。后囊膜混浊(PCO)是主要的术后并发症:单侧白内障患者中为60.0%,双侧白内障患者中为46.3%(P = 0.019)。中位随访时间为2.0年[IQR:1.0 - 5.0]。

结论

先天性白内障手术与早期、认真的弱视治疗相结合时似乎是安全有效的。双侧先天性白内障的视觉效果优于单侧白内障。

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