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免疫功能正常患者的肠炎沙门氏菌血清型肠炎伴自发性肠穿孔腹膜炎

serovar enteritidis peritonitis with spontaneous intestinal perforation in an immunocompetent patient.

作者信息

Hélias Marion, Planchon Jérôme, Bousquet Aurore, Dubost Clément

机构信息

Hopital d'Instruction des Armees Begin, Saint Mande, France.

出版信息

BMJ Case Rep. 2019 Mar 20;12(3):e228027. doi: 10.1136/bcr-2018-228027.

Abstract

Few data reported non-typhoidal peritonitis in immunocompromised patients. We reported the case of a man without immunosuppression or predisposing factor, who developed serovar Enteritidis peritonitis with spontaneous intestinal perforation. After emergent surgery, the patient was transferred to intensive care unit (ICU) because of respiratory, renal and haemodynamic failures. When serovar Enteritidis was identified, antibiotics were de-escalated for ceftriaxone and metronidazole for 5 days. No immunosuppression was found. Evolution was favourable, and the patient has been discharged from the ICU on day 8. The originality of this case arises from a perforation peritonitis secondary to without any immunosuppression. In absence of non-Typhi data, we treated this patient as a typhoid perforation: surgical treatment, antibiotic association and supportive care.

摘要

很少有数据报道免疫功能低下患者发生非伤寒性腹膜炎。我们报告了一例无免疫抑制或易感因素的男性病例,该患者发生了肠炎血清型腹膜炎并伴有自发性肠穿孔。急诊手术后,患者因呼吸、肾脏和血流动力学衰竭被转入重症监护病房(ICU)。当确定为肠炎血清型时,抗生素降级为头孢曲松和甲硝唑,使用5天。未发现免疫抑制情况。病情进展良好,患者于第8天从ICU出院。该病例的独特之处在于继发于无任何免疫抑制的穿孔性腹膜炎。由于缺乏非伤寒的数据,我们将该患者按照伤寒穿孔进行治疗:手术治疗、联合使用抗生素及支持治疗。

相似文献

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Spontaneous Salmonella peritonitis in HIV infection.HIV感染中的自发性沙门氏菌腹膜炎
J Infect. 1995 Jan;30(1):87-8. doi: 10.1016/s0163-4453(95)93185-6.

本文引用的文献

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Progress in management of typhoid perforation.伤寒穿孔的治疗进展
Ann Afr Med. 2011 Oct-Dec;10(4):259-65. doi: 10.4103/1596-3519.87040.
9
Salmonella infections in immunocompromised adults.免疫功能低下成人中的沙门氏菌感染。
J Infect. 2008 Jun;56(6):413-22. doi: 10.1016/j.jinf.2008.03.012. Epub 2008 May 12.

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