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维生素D在老年炎症性肠病患者中的作用

The Role of Vitamin D in Elderly Inflammatory Bowel Disease Patients.

作者信息

Kagolanu Deepthi, Levine Irving, Katz Seymour

机构信息

Dr Kagolanu is a medical resident in the Department of Internal Medicine at Nassau University Medical Center in East Meadow, New York.

Dr Levine is a medical resident in the Department of Internal Medicine at NYU Langone Health in New York, New York.

出版信息

Gastroenterol Hepatol (N Y). 2019 Jan;15(1):28-34.

PMID:30899205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6423690/
Abstract

The role of vitamin D has long been discussed in many chronic diseases, and its significance in inflammatory bowel disease has recently gained attention. This article reviews vitamin D homeostasis, the involvement of vitamin D in the pathophysiology of inflammatory bowel disease, and vitamin D deficiency as a result of inflammatory bowel disease. In addition, this article explores the possibility of age, specifically in the elderly population, as a risk factor for developing vitamin D deficiency in patients with inflammatory bowel disease.

摘要

维生素D在多种慢性疾病中的作用长期以来一直被讨论,其在炎症性肠病中的意义最近受到了关注。本文综述了维生素D稳态、维生素D在炎症性肠病病理生理学中的作用以及炎症性肠病导致的维生素D缺乏。此外,本文还探讨了年龄,特别是老年人群,作为炎症性肠病患者发生维生素D缺乏风险因素的可能性。

相似文献

1
The Role of Vitamin D in Elderly Inflammatory Bowel Disease Patients.维生素D在老年炎症性肠病患者中的作用
Gastroenterol Hepatol (N Y). 2019 Jan;15(1):28-34.
2
Vitamin D in Inflammatory Bowel Disease: Biological, Clinical and Therapeutic Aspects.炎症性肠病中的维生素 D:生物学、临床和治疗方面。
Curr Drug Metab. 2019;20(5):390-398. doi: 10.2174/1389200220666190520112003.
3
Vitamin D status in children and young adults with inflammatory bowel disease.炎症性肠病患儿及青年成人的维生素D状况
Pediatrics. 2006 Nov;118(5):1950-61. doi: 10.1542/peds.2006-0841.
4
Vitamin D deficiency in patients with either rheumatic diseases or inflammatory bowel diseases on biologic therapy.接受生物治疗的风湿性疾病或炎症性肠病患者的维生素D缺乏症。
Intern Emerg Med. 2016 Sep;11(6):803-7. doi: 10.1007/s11739-016-1415-9. Epub 2016 Mar 3.
5
Mechanisms of disease: vitamin D and inflammatory bowel disease.疾病机制:维生素D与炎症性肠病
Nat Clin Pract Gastroenterol Hepatol. 2005 Jul;2(7):308-15. doi: 10.1038/ncpgasthep0215.
6
Vitamin D deficiency in patients with inflammatory bowel disease.炎症性肠病患者的维生素D缺乏症
Br J Nurs. 2016 Aug 11;25(15):846-51. doi: 10.12968/bjon.2016.25.15.846.
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Differences in outcomes between cholecalciferol and ergocalciferol supplementation in veterans with inflammatory bowel disease.维生素 D2 和维生素 D3 补充剂对炎症性肠病退伍军人的疗效差异。
Geriatr Gerontol Int. 2012 Jul;12(3):475-80. doi: 10.1111/j.1447-0594.2011.00798.x. Epub 2012 Jan 10.
8
Vitamin D and the Pathogenesis of Inflammatory Bowel Disease.维生素D与炎症性肠病的发病机制
Curr Gastroenterol Rep. 2016 Oct;18(10):52. doi: 10.1007/s11894-016-0526-9.
9
Managing vitamin D deficiency in inflammatory bowel disease.炎症性肠病中维生素D缺乏的管理。
Frontline Gastroenterol. 2019 Oct;10(4):394-400. doi: 10.1136/flgastro-2018-101055. Epub 2019 Jan 7.
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Vitamin D and inflammatory diseases.维生素 D 与炎症性疾病。
J Inflamm Res. 2014 May 29;7:69-87. doi: 10.2147/JIR.S63898. eCollection 2014.

本文引用的文献

1
Vitamin D status and its management for achieving optimal health benefits in the elderly.维生素D状况及其管理对老年人实现最佳健康效益的作用。
Expert Rev Endocrinol Metab. 2018 Nov;13(6):279-293. doi: 10.1080/17446651.2018.1533401. Epub 2018 Oct 14.
2
Vitamin D deficiency is associated with disease activity in patients with Crohn's disease.维生素D缺乏与克罗恩病患者的疾病活动相关。
Intest Res. 2019 Jan;17(1):70-77. doi: 10.5217/ir.2018.00022. Epub 2018 Oct 10.
3
High Prevalence of Vitamin D Deficiency among Patients with Inflammatory Bowel Disease.炎症性肠病患者中维生素D缺乏的高患病率。
Inflamm Intest Dis. 2018 Jul;2(4):200-210. doi: 10.1159/000489010. Epub 2018 Jun 28.
4
The Role of Vitamin D in Brain Health: A Mini Literature Review.维生素D在脑健康中的作用:一篇小型文献综述
Cureus. 2018 Jul 10;10(7):e2960. doi: 10.7759/cureus.2960.
5
Vitamin D, the gut microbiome and inflammatory bowel disease.维生素D、肠道微生物群与炎症性肠病
J Res Med Sci. 2018 Aug 23;23:75. doi: 10.4103/jrms.JRMS_606_17. eCollection 2018.
6
Vitamin D: a brief overview of its importance and role in inflammatory bowel disease.维生素D:其在炎症性肠病中的重要性及作用概述
Transl Gastroenterol Hepatol. 2018 May 29;3:31. doi: 10.21037/tgh.2018.05.03. eCollection 2018.
7
Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts.循环维生素 D 与结直肠癌风险:17 项队列国际汇总研究。
J Natl Cancer Inst. 2019 Feb 1;111(2):158-169. doi: 10.1093/jnci/djy087.
8
The When, What & How of Measuring Vitamin D Metabolism in Clinical Medicine.维生素 D 代谢在临床医学中的测量时机、方法和内容
Nutrients. 2018 Apr 13;10(4):482. doi: 10.3390/nu10040482.
9
Prediagnostic Serum Vitamin D Levels and the Risk of Crohn's Disease and Ulcerative Colitis in European Populations: A Nested Case-Control Study.欧洲人群中诊断前血清维生素 D 水平与克罗恩病和溃疡性结肠炎风险的关系:巢式病例对照研究。
Inflamm Bowel Dis. 2018 Feb 15;24(3):633-640. doi: 10.1093/ibd/izx050.
10
Calcium and vitamin D in human health: Hype or real?钙和维生素 D 与人类健康:炒作还是真实?
J Steroid Biochem Mol Biol. 2018 Jun;180:4-14. doi: 10.1016/j.jsbmb.2017.12.009. Epub 2017 Dec 16.