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早期取出双J管是否能降低活体供肾移植受者的泌尿系统感染率?

Does early removal of double J stents reduce urinary infection in living donor renal transplantation?

作者信息

Soylu Lutfi, Aydin Oguz Ugur, Atli Muzaffet, Gunt Ceren, Ekmekci Yakup, Cekmen Nedim, Karademir Sedat

机构信息

Department of General Surgery and Organ Transplantation, Ankara Güven Hastanesi, Ankara, Turkey.

Department of Anesthesiology and Reanimation, Ankara Güven Hastanesi, Ankara, Turkey.

出版信息

Arch Med Sci. 2019 Mar;15(2):402-407. doi: 10.5114/aoms.2018.73524. Epub 2018 Feb 15.

Abstract

INTRODUCTION

Prophylactic use of double J (DJ) stents in recipients is highly accepted in renal transplantation. In this study, the association between the frequency of urologic complications (UC) and urinary tract infections (UTI), and the early or late removal of DJ stents was investigated.

MATERIAL AND METHODS

A total of 116 live-donor renal transplant patients were included in the study during a 4-year period, with a mean follow-up of 29.2 ±15.3 months. In all, DJ stents were used. All patients were clinically monitored for graft function by assessment of the complete blood count, renal biochemistry, urine analysis and blood drug level according to our follow-up protocol.

RESULTS

The patients were divided into 2 groups according to the time of their stent removal: group I ( = 44), removal within the first 14 days; and group II ( = 72), removal after 14 days. No urinary leaks were detected in either of the groups. Three patients suffered from anastomotic stricture (group I, = 1; group II, = 2). The rates of UTI were similar in groups I and II (13.6% vs. 16.6%, respectively, = 0.79). The rate of UTI in women was found to be 3.8 times higher than in men.

CONCLUSIONS

The results of our study demonstrated that DJ stent removal within 14 days did not reduce the risk of UTI when compared to stent removal after 14 days. Similar effects on complication rates for ureteral stenting for these 2 removal periods were observed.

摘要

引言

在肾移植受者中预防性使用双J(DJ)支架已被广泛接受。本研究调查了泌尿系统并发症(UC)和尿路感染(UTI)的发生频率与DJ支架早期或晚期取出之间的关联。

材料与方法

在4年期间,共有116例活体供肾肾移植患者纳入本研究,平均随访时间为29.2±15.3个月。所有患者均使用了DJ支架。根据我们的随访方案,通过评估全血细胞计数、肾脏生化指标、尿液分析和血药浓度对所有患者的移植肾功能进行临床监测。

结果

根据支架取出时间将患者分为2组:第一组(n = 44),在14天内取出;第二组(n = 72),在14天后取出。两组均未检测到尿漏。3例患者出现吻合口狭窄(第一组,n = 1;第二组,n = 2)。第一组和第二组的UTI发生率相似(分别为13.6%和16.6%,P = 0.79)。发现女性UTI发生率比男性高3.8倍。

结论

我们的研究结果表明,与14天后取出支架相比,14天内取出DJ支架并未降低UTI风险。观察到这两个取出时间段对输尿管支架置入并发症发生率的影响相似。

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