Shohab Durre, Khawaja Athar, Atif Emad, Jamil Imran, Ali Iftikhar, Akhter Saeed
Department of Urology and Kidney Transplant, Pakistan Kidney Institute, Shifa International Hospital, Islamabad, Pakistan.
Saudi J Kidney Dis Transpl. 2015 May-Jun;26(3):443-6. doi: 10.4103/1319-2442.157298.
Prophylactic ureteric stenting in renal transplant recipients prevents major surgical complications such as ureteric leak and obstruction on the one hand while, on the other hand, it is associated with complications like urinary tract infections (UTI), hematuria, stent migration, stent encrustation and forgotten stents. UTI is documented to be most common complication associated with double J (DJ) stent. In this retrospective observational study involving 157 patients, we compared the frequency of occurrence of UTI in DJ-stented versus non-stented renal transplant recipients. The study patients had undergone renal transplantation, with or without DJ-stenting, between January 2007 and June 2012. The mean age of the study subjects was 34.01 ± 14.63 years. The patients were followed-up for one year post-transplantation with regular evaluation, including detailed assessment, complete blood picture, renal function tests, routine urine examination and cultures. Data were collected through chart and electronic record review. Of a total of 157 patients, 61 (38.85%) developed UTI, including 30 of 74 stented patients (40.54%) and 31 of 83 non-stented renal transplant recipients (37.34%). Relative risk was calculated to be 1.08. The mean serum creatinine at the end of one year was 1.47 mg/dL in DJ-stented patients and 1.36 mg/dL in nonstented patients. Our study suggests that there is no significant difference in the frequency of UTI between DJ-stented and non-stented renal transplant recipients.
肾移植受者预防性输尿管支架置入术一方面可预防输尿管漏和梗阻等主要手术并发症，另一方面却与诸如尿路感染（UTI）、血尿、支架移位、支架结痂和遗忘支架等并发症相关。据记载，UTI是与双J（DJ）支架相关的最常见并发症。在这项涉及157例患者的回顾性观察研究中，我们比较了置入DJ支架与未置入支架的肾移植受者发生UTI的频率。研究患者在2007年1月至2012年6月期间接受了肾移植，无论是否置入DJ支架。研究对象的平均年龄为34.01±14.63岁。患者在移植后接受了一年的随访，并进行定期评估，包括详细评估、全血细胞计数、肾功能检查、尿常规检查和培养。数据通过病历和电子记录审查收集。在总共157例患者中，61例（38.85%）发生了UTI，其中74例置入支架的患者中有30例（40.54%），83例未置入支架的肾移植受者中有31例（37.34%）。计算得出相对风险为1.08。一年结束时，置入DJ支架的患者平均血清肌酐为1.47mg/dL，未置入支架的患者为1.36mg/dL。我们的研究表明，置入DJ支架与未置入支架的肾移植受者发生UTI的频率没有显著差异。
