Powell C R
Indiana University Department of Urology.
Curr Bladder Dysfunct Rep. 2013 Dec;8(4):282-288. doi: 10.1007/s11884-013-0199-2. Epub 2013 Aug 25.
Although neuromodulation is well established for the treatment of non-neurogenic lower urinary tract symptoms, recent literature supports its use in the patient having LUTS associated with a neurologic condition. Sacral neuromodulation, in particular, may see new use as a modality to facilitate neurologic remodeling in spinal cord injured patients as well as children. As a therapeutic option, sacral neuromodulation and dorsal genital nerve stimulation may one day become more effective and more efficient utilizing the concept of closed-loop feedback, where electro-neurogram and bladder pressure data are incorporated into stimulation routines. In addition, some older therapies are reviewed that have recently demonstrated success in this patient population.
虽然神经调节在治疗非神经源性下尿路症状方面已得到充分确立,但最近的文献支持其在患有与神经系统疾病相关的下尿路症状的患者中的应用。特别是骶神经调节,可能会有新的用途,作为一种促进脊髓损伤患者以及儿童神经重塑的方式。作为一种治疗选择,骶神经调节和阴部神经背侧刺激有朝一日可能会利用闭环反馈的概念变得更有效、更高效,即将神经电图和膀胱压力数据纳入刺激程序中。此外,还回顾了一些较古老的疗法,这些疗法最近在这一患者群体中取得了成功。