Cho Kang Hee, Lee Sang Sook
Department of Rehabilitation Medicine, Chungnam National University School of Medicine, Daejeon 301-172, Korea.
Ann Rehabil Med. 2012 Apr;36(2):213-9. doi: 10.5535/arm.2012.36.2.213. Epub 2012 Apr 30.
To investigate the effect of radiofrequency (RF) sacral rhizotomy of the intolerable neurogenic bladder in spinal cord injured patients.
Percutaneous RF sacral rhizotomy was performed on 12 spinal cord injured patients who had neurogenic bladder manifested with urinary incontinence resisted to an oral and intravesical anticholinergic instillation treatment. Various combinations of S2, S3, and S4 RF rhizotomies were performed. The urodynamic study (UDS) was performed 1 week before RF rhizotomy. The voiding cystourethrogram (VCUG) and voiding diaries were compared 1 week before and 4 weeks after therapy. Total volume of daily urinary incontinence (ml/day) and clean intermittent catheterization (ml/time) volume of each time were also monitored.
After RF sacral rhizotomy, bladder capacity increased in 9 patients and the amount of daily urinary incontinence decreased in 11 patients. The mean maximal bladder capacity increased from 292.5 to 383.3 ml (p<0.05) and mean daily incontinent volume decreased from 255 to 65 ml (p<0.05). Bladder trabeculation and vesicoureteral reflux findings did not change 4 weeks after therapy.
This study revealed that RF sacral rhizotomy was an effective method for neurogenic bladder with uncontrolled incontinence using conventional therapy among spinal cord injured patients.
探讨射频(RF)骶神经根切断术对脊髓损伤患者难以耐受的神经源性膀胱的影响。
对12例脊髓损伤后神经源性膀胱且口服及膀胱内抗胆碱能药物灌注治疗无效、表现为尿失禁的患者实施经皮RF骶神经根切断术。进行了S2、S3和S4神经根切断术的不同组合。在RF神经根切断术前1周进行尿动力学研究(UDS)。比较治疗前1周和治疗后4周的排尿性膀胱尿道造影(VCUG)及排尿日记。还监测每日尿失禁总量(毫升/天)及每次清洁间歇性导尿(毫升/次)量。
RF骶神经根切断术后,9例患者膀胱容量增加,11例患者每日尿失禁量减少。平均最大膀胱容量从292.5毫升增加至383.3毫升(p<0.05),平均每日失禁量从255毫升降至65毫升(p<0.05)。治疗4周后膀胱小梁形成及膀胱输尿管反流情况未改变。
本研究表明,RF骶神经根切断术是脊髓损伤患者中对于采用传统治疗方法无法控制的尿失禁神经源性膀胱的一种有效治疗方法。