Department of Internal Medicine, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Department of Microbiology, Hospital Universitario de Guadalajara, Guadalajara, Spain.
J Med Virol. 2019 Sep;91(9):1679-1683. doi: 10.1002/jmv.25462. Epub 2019 Apr 1.
Our objective is to assess the characteristics of respiratory syncytial virus (RSV) infection in adult patients and to establish differences with influenza viruses. Fifty-four patients diagnosed with RSV and 198 with influenza were prospectively included. Compared with influenza, empirical antimicrobial therapy was more frequent in patients diagnosed with RSV, whereas antibiotic withdrawal at the time of diagnosis confirmation was lower (OR, 0.12; CI, 95% 0.01-0.90; P = 0.040). RSV-positive patients were more likely to need hospital readmission (OR, 3.00; CI, 95% 0.98-9.09; P = 0.053). The role of RSV infection in adults is often overlooked, leading to inappropriate use of antibiotics and a probable increase in nosocomial RSV transmission.
我们的目的是评估成人呼吸道合胞病毒（RSV）感染的特征，并与流感病毒进行比较。前瞻性纳入了 54 例确诊为 RSV 感染的患者和 198 例流感患者。与流感相比，RSV 感染患者更常接受经验性抗菌治疗，而在确诊时停用抗生素的比例较低（OR，0.12；95%CI，0.01-0.90；P=0.040）。RSV 阳性患者更有可能需要再次住院治疗（OR，3.00；95%CI，0.98-9.09；P=0.053）。成人 RSV 感染常常被忽视，导致抗生素使用不当，并可能增加医院内 RSV 的传播。
