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Antimalarial stewardship programs are urgently needed for malaria elimination: a perspective.

作者信息

Bienvenu Anne-Lise, Djimdé Abdoulaye, Picot Stéphane

机构信息

Groupement Hospitalier Nord, Service Pharmacie, Hospices Civils de Lyon, Lyon, F-69004, France - ICBMS CNRS 5246, SMITh, Malaria Research Unit, Campus Lyon-Tech La Doua, Université de Lyon, Villeurbanne, F-69100, France.

Malaria Research and Training Center, University of Sciences, Techniques and Technologies of Bamako, PO Box: 1805 Point G, Bamako, Mali.

出版信息

Parasite. 2019;26:16. doi: 10.1051/parasite/2019016. Epub 2019 Mar 22.

DOI:10.1051/parasite/2019016
PMID:30901307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6430615/
Abstract

Global malaria cases have not been significantly reduced over the last three years although more than USD 3 billion was invested in malaria control and elimination. The reasons for this stagnation are highly complex and multi-factorial. It remains that almost three billion treatment courses were supplied over the period 2010-2017: 30% of them without malaria tests, and some with suboptimal doses leading to the risk of selection of resistant parasites. An antimalarial stewardship program should be implemented at the healthcare provider, physician, pharmacist, medical student, and population levels. This would significantly reinforce the impact of international guidelines and national malaria program policies and fill the gap between recommendations and actual practices.

摘要

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Infect Control Hosp Epidemiol. 2019 Apr;40(4):432-437. doi: 10.1017/ice.2019.9. Epub 2019 Feb 20.
2
Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination.恶性疟原虫对青蒿素联合疗法的耐药性:疟疾消除之路上的达摩克利斯之剑。
Parasite. 2018;25:24. doi: 10.1051/parasite/2018021. Epub 2018 Apr 20.
3
A systematic review of interventions and performance measures for antifungal stewardship programmes.抗真菌药物管理计划的干预措施和绩效措施的系统评价。
J Antimicrob Chemother. 2018 Feb 1;73(2):297-305. doi: 10.1093/jac/dkx388.
4
The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study.大湄公河次区域青蒿素耐药恶性疟原虫的传播:一项分子流行病学观察性研究。
Lancet Infect Dis. 2017 May;17(5):491-497. doi: 10.1016/S1473-3099(17)30048-8. Epub 2017 Feb 2.
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