言语治疗对语言障碍患者P300结果的影响：一项荟萃分析。
Influence of speech-language therapy on P300 outcome in patients with language disorders: a meta-analysis.
作者信息
Silva Deise Renata Oliveira da, Menezes Pedro de Lemos, Almeida Grazielle de Farias, Souza Thais Nobre Uchoa, Costa Ranilde Cristiane Cavalcante, Frizzo Ana Claudia Figueiredo, Carnaúba Aline Tenório Lins
机构信息
Universidade Estadual de Ciências da Saúde de Alagoas (UNCISAL), Maceió, AL, Brazil.
Universidade Estadual de Ciências da Saúde de Alagoas (UNCISAL), Maceió, AL, Brazil; Universidade de São Paulo (USP), Física Aplicada à Medicina, São Paulo, SP, Brazil.
出版信息
Braz J Otorhinolaryngol. 2019 Jul-Aug;85(4):510-519. doi: 10.1016/j.bjorl.2019.01.012. Epub 2019 Mar 8.
INTRODUCTION
The patient's evolution in the audiology and speech-language clinic acts as a motivator of the therapeutic process, contributing to patient adherence to the treatment and allowing the therapist to review and/or maintain their clinical therapeutic conducts. Electrophysiological measures, such as the P300 evoked potential, help in the evaluation, understanding and monitoring of human communication disorders, thus facilitating the prognosis definition in each case.
OBJECTIVE
To determine whether the audiology and speech-language therapy influences the variation of P300 latency and amplitude in patients with speech disorders undergoing speech therapy.
METHODS
This is a systematic review with meta-analysis, in which the following databases were searched: Pubmed, ScienceDirect, SCOPUS, Web of Science, SciELO and LILACS, in addition to the gray literature bases: OpenGrey.eu and DissOnline. The inclusion criteria were randomized or non-randomized clinical trials, without language or date restriction, which evaluated children with language disorders undergoing speech therapy, monitored by P300, compared to children without intervention.
RESULTS
The mean difference between the latencies in the group submitted to therapy and the control group was -20.12ms with a 95% confidence interval of -43.98 to 3.74ms (p=0.08, I=25% and p value=0.26). The mean difference between the amplitudes of the group submitted to therapy and the control group was 0.73uV with a 95% confidence interval of -1.77 to 3.23uV (p=0.57, I=0% and p value=0.47).
CONCLUSION
The present meta-analysis demonstrates that speech therapy does not influence the latency and amplitude results of the P300 evoked potential in children undergoing speech therapy intervention.
引言
患者在听力学和言语语言诊所的进展是治疗过程的一个激励因素，有助于患者坚持治疗，并使治疗师能够回顾和/或维持他们的临床治疗行为。电生理测量，如P300诱发电位，有助于评估、理解和监测人类交流障碍，从而便于确定每种情况下的预后。
目的
确定听力学和言语语言治疗是否会影响接受言语治疗的言语障碍患者P300潜伏期和波幅的变化。
方法
这是一项进行荟萃分析的系统评价，除灰色文献库OpenGrey.eu和DissOnline外，还检索了以下数据库：PubMed、ScienceDirect、SCOPUS、Web of Science、SciELO和LILACS。纳入标准为随机或非随机临床试验，无语言或日期限制，评估接受言语治疗的语言障碍儿童，并通过P300进行监测，与未接受干预的儿童进行比较。
结果
接受治疗组与对照组潜伏期的平均差值为-20.12ms，95%置信区间为-43.98至3.74ms（p=0.08，I=25%，p值=0.26）。接受治疗组与对照组波幅的平均差值为0.73μV，95%置信区间为-1.77至3.23μV（p=0.57，I=0%，p值=0.47）。
结论
本荟萃分析表明，言语治疗不会影响接受言语治疗干预儿童的P300诱发电位潜伏期和波幅结果。
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