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上皮样雪旺细胞瘤:X 线片、MRI 和超声的影像学表现。

Epithelioid schwannoma: imaging findings on radiographs, MRI, and ultrasound.

机构信息

Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

Department of Orthopedic Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

出版信息

Skeletal Radiol. 2019 Nov;48(11):1815-1820. doi: 10.1007/s00256-019-03199-9. Epub 2019 Mar 22.

DOI:10.1007/s00256-019-03199-9
PMID:30903261
Abstract

Epithelioid schwannoma is an uncommon benign peripheral nerve sheath tumor, with distinct morphological and pathological features. To our knowledge, the imaging features of epithelioid schwannoma have not been described. In this case report, we describe the imaging findings of a pathologically proven case of epithelioid schwannoma presenting as a slowly growing painless mass near the ankle. The MR imaging signs commonly associated with conventional schwannoma were absent. On correlative radiographs, there were intra-tumoral calcifications. Radiographs are an essential tool in the imaging evaluation of soft-tissue masses. Knowledge of soft-tissue tumor types that can be associated with intra-tumoral calcifications is helpful in honing the differential diagnosis.

摘要

上皮样 schwann 瘤是一种罕见的良性周围神经鞘瘤,具有独特的形态学和病理学特征。据我们所知,上皮样 schwann 瘤的影像学特征尚未被描述。在本病例报告中,我们描述了一个经病理证实的上皮样 schwann 瘤病例的影像学表现,该病例表现为踝关节附近缓慢生长的无痛性肿块。与常规 schwann 瘤相关的磁共振成像征象均不存在。在相关的 X 线片上,有肿瘤内钙化。X 线片是软组织肿块影像学评估的重要工具。了解可能与肿瘤内钙化相关的软组织肿瘤类型有助于进行鉴别诊断。

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本文引用的文献

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SMARCB1/INI1 Loss in Epithelioid Schwannoma: A Clinicopathologic and Immunohistochemical Study of 65 Cases.上皮样神经鞘瘤中SMARCB1/INI1缺失:65例临床病理及免疫组化研究
Am J Surg Pathol. 2017 Aug;41(8):1013-1022. doi: 10.1097/PAS.0000000000000849.
2
Epithelioid Schwannomas: An Analysis of 58 Cases Including Atypical Variants.上皮样神经鞘瘤:58例分析,包括非典型变体
Am J Surg Pathol. 2016 May;40(5):704-13. doi: 10.1097/PAS.0000000000000589.
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Epithelioid Schwannoma of a Spinal Nerve Root.脊神经根上皮样施万细胞瘤
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Epithelioid malignant peripheral nerve sheath tumor: clinicopathologic analysis of 63 cases.上皮样恶性外周神经鞘膜瘤:63例临床病理分析
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Intrathoracic ancient neurilemoma mimicking mesenchymal thoracic tumor.胸腔内古老神经鞘瘤,酷似间叶性胸壁肿瘤。
Am J Med Sci. 2013 Nov;346(5):424-6. doi: 10.1097/MAJ.0b013e3182960b12.
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Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems.周围神经鞘瘤的病理学:诊断概述及部分诊断问题的更新。
Acta Neuropathol. 2012 Mar;123(3):295-319. doi: 10.1007/s00401-012-0954-z. Epub 2012 Feb 12.
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Epithelioid schwannoma of soft tissue: unusual morphological variant causing a diagnostic dilemma.软组织上皮样施万瘤:导致诊断困境的不寻常形态学变异型
Ann Diagn Pathol. 2012 Dec;16(6):521-6. doi: 10.1016/j.anndiagpath.2011.05.003. Epub 2011 Aug 16.
8
The role of the plain radiograph in the characterisation of soft tissue tumours.普通X线片在软组织肿瘤特征描述中的作用。
Skeletal Radiol. 2009 Jun;38(6):549-58. doi: 10.1007/s00256-008-0513-9. Epub 2008 Jun 20.
9
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Benign epithelioid peripheral nerve sheath tumors of the soft tissues: clinicopathologic spectrum of 33 cases.软组织良性上皮样周围神经鞘瘤:33例临床病理分析
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