Fredette Ryan P, Ahn Leah, Towery Emily, Mahvi David A, Salazar Edgar L Martinez
University of Massachusetts Chan Medical School, Worcester, MA, USA.
Department of Radiology, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA, USA.
Skeletal Radiol. 2025 Aug 15. doi: 10.1007/s00256-025-05012-2.
Ossifying fibromyxoid tumors (OFMT) are rare tumors with an intermediate risk of malignancy that are usually found in the extremities. To date, only three cases of OFMTs involving the paraspinal musculature have been reported in the literature. Two of these previously reported cases demonstrated poorly circumscribed tumors with involvement of adjacent osseous and soft tissue structures. We report the first case of a well-circumscribed OFMT involving the paraspinal musculature with extrinsic erosion of bone but otherwise no significant soft tissue extension. Specifically, we review the CT and MRI findings, immunohistopathology, and genetics used to confirm the diagnosis of OFMT.
骨化性纤维黏液样肿瘤(OFMT)是一种罕见的肿瘤,具有中等恶性风险,通常发生于四肢。迄今为止,文献中仅报道了3例累及椎旁肌肉组织的OFMT。之前报道的这些病例中有2例显示肿瘤边界不清,累及相邻的骨质和软组织结构。我们报告首例边界清晰的累及椎旁肌肉组织的OFMT,伴有骨质外生性侵蚀,但无明显的软组织浸润。具体而言,我们回顾了用于确诊OFMT的CT和MRI表现、免疫组织病理学及遗传学特征。