Tumanova U N, Lyapin V M, Bychenko V G, Shchegolev A I, Sukhikh G T
V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
Bull Exp Biol Med. 2019 Mar;166(5):671-675. doi: 10.1007/s10517-019-04415-1. Epub 2019 Mar 22.
We studied the possibilities of postmortem magnetic resonance imaging (MRI) for evaluation of anasarca in newborns. Before the autopsy, MRI in T1 and T2 standard modes was performed, signal intensity tomograms in the subcutaneous tissue were analyzed, and tissue hydration index was calculated. Using 3D reconstruction, we determined the values of hydrothorax, hydropericardium, and ascites, as well as specific volumes of fluid in the abdominal and thoracic cavities. It has been established that postmortem MRI of deceased newborns provides objective quantitative assessment of anasarca, as well as absolute and relative volumes of hydrothorax and ascites, which improves the diagnostic capacities of pathoanatomical autopsy or forensic examination of a corpse and contributes to the determination of tanatogenesis. However, postmortem MRI cannot fully replace traditional autopsy that allows conducting complex macroscopic and microscopic analysis of organs and tissues.
我们研究了新生儿尸检磁共振成像（MRI）用于评估全身性水肿的可能性。在尸检前，以T1和T2标准模式进行MRI检查，分析皮下组织的信号强度断层图像，并计算组织水合指数。通过三维重建，我们确定了胸腔积液、心包积液和腹水的值，以及腹腔和胸腔内液体的比容。已证实，已故新生儿的尸检MRI能够对全身性水肿以及胸腔积液和腹水的绝对和相对体积进行客观定量评估，这提高了尸体病理解剖或法医检查的诊断能力，并有助于确定死因。然而，尸检MRI不能完全取代传统尸检，传统尸检能够对器官和组织进行复杂的宏观和微观分析。
