V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russian Federation, Moscow, Russia.
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
Bull Exp Biol Med. 2021 Jan;170(3):371-377. doi: 10.1007/s10517-021-05070-1. Epub 2021 Jan 16.
Using postmortem MRI, we studied the features of the development of internal cadaveric hypostasis in dead newborns. Postmortem radiological and pathoanatomical examination of 62 bodies of newborns and infants who died at the age of 1.5 h to 49 days was carried out. After the death was ascertained, prior to MRI, the bodies were stored in a refrigerator at 4°C in the supine position. Depending on the duration of the postmortem period (2-72 h), all observations were divided into eight groups. Prior to autopsy, an MRI scan was performed in T1 and T2 standard modes, followed by analysis of the presence and severity of the gradient line of the intensity of the MR signal in the liver and lung tissue in the ventral (overlying) and dorsal (underlying) areas, as well as the presence of a gradient of the intensity of the blood signal in the heart cavity and in the aortic lumen. The main manifestations of cadaveric hypostasis in the liver and lungs are changes of the MR signal intensity in the ventral and dorsal regions with the appearance of a horizontal gradient of the MR signal intensity, which reflects the location of the body after death. In the heart cavity and in the aortic lumen, there is also a gradient of the blood signal intensity of various severity with the visualization of two or three of its layers. The revealed features of the MRI signal intensity and, accordingly, the presence of its horizontal gradient depended not only on the MRI mode of the study, but also on the studied organ and the duration of the postmortem period. This should be taken into account when analyzing the results of virtopsy and determining the links of thanatogenesis of dead newborns and infants.
利用死后磁共振成像（MRI），我们研究了内部尸体尸斑在死亡新生儿中的发展特征。对 62 具在 1.5 小时至 49 天死亡的新生儿和婴儿的尸体进行了死后放射学和病理解剖检查。在确定死亡后，在进行 MRI 之前，将尸体以仰卧位储存在 4°C 的冰箱中。根据死后时间（2-72 小时）的不同，将所有观察结果分为八组。在尸检之前，进行了 T1 和 T2 标准模式的 MRI 扫描，然后分析了肝和肺组织腹侧（覆盖）和背侧（下）区域 MR 信号强度梯度线的存在和严重程度，以及心腔和主动脉腔内血液信号强度梯度的存在。肝和肺尸斑的主要表现是腹侧和背侧区域的 MR 信号强度变化，出现 MR 信号强度的水平梯度，反映了死亡后尸体的位置。在心腔和主动脉腔内，也存在不同严重程度的血液信号强度梯度，可观察到其两到三层。所揭示的 MRI 信号强度特征，以及其水平梯度的存在，不仅取决于研究的 MRI 模式，还取决于所研究的器官和死后时间。在分析虚拟尸检结果并确定死亡新生儿和婴儿的死亡发生环节时，应考虑到这一点。
