Institute of Fluid Mechanics, University of Erlangen-Nuremberg, Campus Busan, Busan, Republic of Korea.
ShapeVision Co., Hwaseong City, Republic of Korea.
Lasers Med Sci. 2019 Dec;34(9):1763-1779. doi: 10.1007/s10103-019-02770-z. Epub 2019 Mar 22.
This study aims to assess whether central-symmetric corneal thickness reduces off-centered corneal shift caused by intraocular pressure (IOP). In this retrospective study, 122 healthy eyes of 62 presbyopic patients, mostly myopic, were divided into two groups. Two distinct asymmetric corneal ablations were applied in peripheral presbyopia correction to produce central-symmetric corneal thickness, which reduces the off-centered corneal shift by utilizing intraocular pressure. The first method used a 90° angled combination in group 1 and the second method used a 45° angled combination in group 2. Target refraction was spherical equivalent of - 1D. Self-developed image processing algorithm analyzed the change in thickness and the posterior cone, and obtained two factors: central symmetry (f) and visual axis deviation (d), from each eye's pre and postoperative maps of Orbscan II. UDVA and UNVA were also analyzed. In both groups, mean SE was about - 1D and there was no significant difference in UDVA. UNVA was better in group 2 than group 1. Only in group 2, corneal thickness and posterior cone became central-symmetric and the posterior corneal apex point relocated towards the visual axis. The p values were 0.03, 0.04, and 0.03, respectively. This is the first study to control corneal shape by utilizing the interaction between intraocular pressure and corneal thickness. Only group 2 was applied with asymmetric corneal ablation created by the 45° angled combination of semi-cylindrical ablation patterns, and intraocular pressure contributed significantly to reduce the off-centered corneal shift and reshaped the posterior corneal cone to the center.
本研究旨在评估角膜厚度的中心对称性是否会减少眼压(IOP)引起的偏心角膜移位。在这项回顾性研究中,将 62 名远视患者的 122 只健康眼分为两组。在外周性远视矫正中应用两种不同的非对称角膜消融术,产生中心对称的角膜厚度,利用眼内压减少偏心角膜移位。第一种方法在第 1 组中使用 90°角组合,第二种方法在第 2 组中使用 45°角组合。目标屈光度为-1D 的球镜等效值。自行开发的图像处理算法分析了厚度和后圆锥的变化,并从 Orbscan II 每个眼睛的术前和术后地图中获得了两个因素:中心对称性(f)和视轴偏差(d)。还分析了 UDVA 和 UNVA。在两组中,平均 SE 约为-1D,UDVA 没有显著差异。与第 1 组相比,第 2 组的 UNVA 更好。仅在第 2 组中,角膜厚度和后圆锥变得中心对称,后角膜顶点向视轴重新定位。p 值分别为 0.03、0.04 和 0.03。这是第一项利用眼压和角膜厚度之间的相互作用来控制角膜形状的研究。仅在第 2 组中应用了 45°角组合的半圆柱形消融模式产生的非对称角膜消融术,眼压对减少偏心角膜移位和重塑后角膜圆锥到中心有显著贡献。