多羟基生物碱对哺乳动物消化双糖酶的抑制作用。
Inhibition of mammalian digestive disaccharidases by polyhydroxy alkaloids.
作者信息
Scofield A M, Fellows L E, Nash R J, Fleet G W
出版信息
Life Sci. 1986 Aug 18;39(7):645-50. doi: 10.1016/0024-3205(86)90046-9.
PMID:3090396
Abstract
Several polyhydroxy alkaloids, including the eight presently known to occur in plants, have been compared as inhibitors of mouse gut digestive disaccharidases. The indolizidine castanospermine inhibited all activities tested, but others showed a selectivity which could be of value in studies of carbohydrate digestion and errors of metabolism.
摘要
几种多羟基生物碱，包括目前已知存在于植物中的8种，已被作为小鼠肠道消化双糖酶抑制剂进行了比较。吲哚里西啶类的栗精胺抑制了所有测试的活性，但其他生物碱表现出选择性，这在碳水化合物消化和代谢紊乱的研究中可能具有价值。
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