Madden Kenneth M, Feldman Boris, Meneilly Graydon S
Gerontology and Diabetes Research Laboratory, Division of Geriatric Medicine, Department of Medicine and Centre for Hip Health and Mobility, University of British Columbia, Vancouver BC.
Clin Invest Med. 2019 Mar 23;42(1):E39-E46. doi: 10.25011/cim.v42i1.32391.
Postprandial hypotension (PPH) is a serious condition that has been shown to be an independent risk factor for falls, fractures and death.
The prevalence of this problem in older adults with a past history of falls has shown a wide variability in the literature; the present study seeks to examine how the frequency with which blood pressure is measured impacts the prevalence and severity of PPH.
Older adults were recruited sequentially from a geriatric medicine falls clinic for meal testing (n=95). All subjects (mean age 77.5±0.7 years, 61±5% female) were fasting prior to each 90 min standardized meal test. A Finometer (Finapres Medical Systems BV) was used to monitor blood pressure. Beat-by-beat systolic (SBP) measures were averaged for 0.5, 1, 2, 3, 5, 6, 9, 10, 15, 18, 30, 45 and 90 min respectively during the meal test.
Using the original diagnostic method of checking mean blood pressure every 10 min resulted in a PPH prevalence of 42.1±5.1% in our population, with an overall range from 81.1±4.0% to 11.6±3.3% depending on the frequency of calculating SBP. The maximal observed postprandial decrease in SBP also showed a significant difference with blood pressure measurement frequency (p.
餐后低血压(PPH)是一种严重病症,已被证明是跌倒、骨折和死亡的独立危险因素。
既往有跌倒史的老年人中该问题的患病率在文献中差异很大;本研究旨在探讨血压测量频率如何影响PPH的患病率和严重程度。
从老年医学跌倒门诊依次招募老年人进行进餐测试(n = 95)。在每次90分钟的标准化进餐测试前,所有受试者(平均年龄77.5±0.7岁,61±5%为女性)均处于禁食状态。使用Finometer(Finapres Medical Systems BV)监测血压。在进餐测试期间,逐搏收缩压(SBP)测量值分别在0.5、1、2、3、5、6、9、10、15、18、30、45和90分钟进行平均。
使用每10分钟检查一次平均血压的原始诊断方法,我们研究人群中的PPH患病率为42.1±5.1%,根据收缩压计算频率的不同,总体范围从81.1±4.0%到11.6±3.3%。观察到的餐后收缩压最大降幅也因血压测量频率而有显著差异(p.