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加强生物医学和环境研究之间的联系具有良好的临床、科学和社会原因。

There are good clinical, scientific, and social reasons to strengthen links between biomedical and environmental research.

机构信息

Hospital del Mar Medical Research Institute (IMIM PSMar PRBB), Barcelona, Catalonia, Spain; Centro de Investigación Biomédica en Red - Epidemiología y Salud Pública (CIBERESP), Spain; School of Medicine, Universitat Autònoma de Barcelona, Spain; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, North Carolina.

School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA.

出版信息

J Clin Epidemiol. 2019 Jul;111:124-126. doi: 10.1016/j.jclinepi.2019.03.009. Epub 2019 Mar 21.

DOI:10.1016/j.jclinepi.2019.03.009
PMID:30905697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6664300/
Abstract

Clinical epidemiology rarely addresses biological, clinical, epidemiological, environmental, economic, and other social and scientific issues posed by environmental chemical contaminants such as endocrine-disrupting chemicals. There is a considerable gap between research and practice in clinical medicine and in environmental health. Organizations often fail to appreciate the human and economic costs of the diseases that environmental chemical contaminants contribute to cause. Also, the relative lack of attention to environmental causes of disease by researchers in medicine and clinical epidemiology cannot be explained just on scientific grounds. Many scientists have shown the virtues of integrative research. Knowledge on the causes of disease is often secondary in clinical practice, but in other instances, to help patients, clinicians tackle causes of diseases. We can better address how environmental contaminants influence negatively not just the occurrence of disease but its course. To do so, we can generate better evidence and strengthen the social conversation on environmental influences on all dimensions of health and disease.

摘要

临床流行病学很少涉及到生物、临床、流行病学、环境、经济和其他社会及科学问题,如内分泌干扰化学污染物。临床医学和环境卫生研究与实践之间存在相当大的差距。各组织往往没有意识到环境化学污染物导致的疾病的人力和经济成本。此外,医学和临床流行病学研究人员对环境致病原因相对缺乏关注,这不能仅仅从科学角度来解释。许多科学家已经展示了综合研究的优点。在临床实践中,疾病病因的知识往往是次要的,但在其他情况下,为了帮助患者,临床医生会针对病因进行治疗。我们可以更好地了解环境污染物如何不仅对疾病的发生,而且对疾病的进程产生负面影响。为此,我们可以生成更好的证据,并加强关于环境对健康和疾病各个方面影响的社会对话。

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本文引用的文献

1
Metabolism Disrupting Chemicals and Alteration of Neuroendocrine Circuits Controlling Food Intake and Energy Metabolism.代谢干扰化学物质与控制食物摄入和能量代谢的神经内分泌回路改变
Front Endocrinol (Lausanne). 2019 Jan 9;9:766. doi: 10.3389/fendo.2018.00766. eCollection 2018.
2
Firm human evidence on harms of endocrine-disrupting chemicals was unlikely to be obtainable for methodological reasons.由于方法学的原因,不太可能获得关于内分泌干扰化学物质危害的可靠人体证据。
J Clin Epidemiol. 2019 Mar;107:107-115. doi: 10.1016/j.jclinepi.2018.12.005. Epub 2018 Dec 10.
3
Racial/ethnic disparities in disease burden and costs related to exposure to endocrine-disrupting chemicals in the United States: an exploratory analysis.美国因接触内分泌干扰化学物质而导致的疾病负担和费用方面的种族/民族差异:一项探索性分析。
J Clin Epidemiol. 2019 Apr;108:34-43. doi: 10.1016/j.jclinepi.2018.11.024. Epub 2018 Dec 7.
4
In-utero and childhood chemical exposome in six European mother-child cohorts.在六个欧洲母婴队列中进行宫内和儿童期化学暴露组学研究。
Environ Int. 2018 Dec;121(Pt 1):751-763. doi: 10.1016/j.envint.2018.09.056. Epub 2018 Oct 14.
5
Phthalate metabolites in 24-h urine samples of the German Environmental Specimen Bank (ESB) from 1988 to 2015 and a comparison with US NHANES data from 1999 to 2012.2015 年德国环境标本库(ESB)1988 年至 24 小时尿液样本中的邻苯二甲酸代谢物及其与 1999 年至 2012 年美国 NHANES 数据的比较。
Int J Hyg Environ Health. 2017 Mar;220(2 Pt A):130-141. doi: 10.1016/j.ijheh.2016.11.003. Epub 2016 Nov 9.
6
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7
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8
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9
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