[The level and immunochemical characteristics of fibronectin in the plasma of irradiated rats].

The electrophoretic and immunoelectrophoretic methods were used to study fibronectin of blood plasma of intact Wistar rats and of those exposed to 1-10 Gy radiation. The increase in the fibronectin concentration 3 days after irradiation was a function of radiation dose. Possible mechanisms of the hyperfibronectinemia development involving mechanisms of endogenous proteolytic fragmentation of glycoprotein, the increase in the protein synthesis and complexation and inhibition of the rate of fibronectin degradation and elimination are discussed.