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卡压性神经病:头痛发病机制与治疗的概念——一篇叙述性综述

Entrapment Neuropathy: A Concept for Pathogenesis and Treatment of Headaches-A Narrative Review.

作者信息

de Ru J Alexander, Filipovic Boris, Lans Jonathan, van der Veen Erwin L, Lohuis Peter Jfm

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, Central Military Hospital 'Dr. A. Mathijsen', Utrecht, The Netherlands.

Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital Sveti Duh, Zagreb, Croatia.

出版信息

Clin Med Insights Ear Nose Throat. 2019 Mar 15;12:1179550619834949. doi: 10.1177/1179550619834949. eCollection 2019.

Abstract

Entrapment neuropathy is a known cause of neurological disorders. In the head and neck area, this pathophysiological mechanism could be a trigger for headache. Over the last few decades, injection of botulinum toxin type A in the muscles that are causing the compression as well as surgical decompression have proved to be effective treatment methods worldwide for large numbers of patients with daily headaches. In particular the entrapment of the supraorbital nerves in the glabellar musculature and the occipital nerves in the neck musculature are triggers for headache disorders for which many patients are still seeking an effective treatment. This article reviews the literature and aims to bring the concept of neural entrapment to the attention of a wider audience. By doing so, we hope to give more exposure to an effective and relatively safe headache treatment.

摘要

卡压性神经病是已知的神经障碍病因。在头颈部区域,这种病理生理机制可能是头痛的诱因。在过去几十年中,向造成压迫的肌肉注射A型肉毒杆菌毒素以及手术减压,已被证明是全球范围内对大量每日头痛患者有效的治疗方法。特别是眉间肌中上眶上神经的卡压以及颈部肌肉中枕神经的卡压,是许多患者仍在寻求有效治疗的头痛障碍的诱因。本文回顾了相关文献,旨在让更广泛的受众关注神经卡压的概念。通过这样做,我们希望能让一种有效且相对安全的头痛治疗方法得到更多关注。

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