Potsangbam Dhakeswar Singh, Akoijam Babie Anand
Department of Otorhinolaryngology, J N Institute of Medical Sciences, Imphal, Manipur 795005 India.
Indian J Otolaryngol Head Neck Surg. 2019 Mar;71(1):54-59. doi: 10.1007/s12070-018-1518-x. Epub 2018 Oct 30.
This was a randomized clinical trial, of thirty-two patients undergoing endoscopic ossiculoplasty, as a second look surgery, at 6 months after primary endoscopic cholesteatoma surgery, in a duration of 9 years. All patients underwent trans-canal endoscopic ossiculoplasty under local anesthesia. Prosthesis used were (1) Titanium partial ossicular replacement prosthesis (PORP) in fourteen, (2) Titanium total ossicular replacement prosthesis (TORP) in six and (3) Autologous cartilage in twelve cases. Puretone audiometry (PTA) were done preoperatively and postoperatively at 2 months and 3 years. Out of twenty-four cases, which presented only with stapes superstructure; fourteen underwent PORP ossiculoplasty and twelve had cartilage short columella ossiculoplasty (SCC). Out of eight cases, which had only mobile stapes footplate, six underwent TORP ossiculoplasty and only two underwent long columella cartilage ossiculoplasty (LCC). Pre-operative average air conduction threshold (AC) of pure tone audiometry were 45.47 dB (PORP), 66.10 dB (TORP), 49.15 dB (SCC) and 59.15 dB (LCC) groups. The post-operative AC at 2 months were respectively 27.37 dB (PORP), 45.83 dB (TORP), 29.99 dB (SCC) and 39.15 dB (LCC) groups. The gap of air and bone conduction (ABG) at 2 months post-operative stage were 19.05 dB (PORP), 20 dB (TORP), 20.32 dB (SCC) and 39.15 dB (LCC) groups and not much changed after 3 years. Extrusion occurred in three PORPs and four TORPs at 4-8 years after surgery. Four cases were lost to follow up. No extrusion occurred in cartilage ossiculoplasty. Trans-canal endoscopic autologous cartilage ossiculoplasty shows encouraging results comparable to titanium prosthesis in repairing ossicles in cholesteatoma disease.
这是一项随机临床试验,在9年的时间里,对32例在初次内镜下胆脂瘤手术后6个月接受内镜听骨成形术作为二次手术的患者进行了研究。所有患者均在局部麻醉下接受经耳道内镜听骨成形术。使用的假体包括:(1)14例使用钛质部分听骨置换假体(PORP);(2)6例使用钛质全听骨置换假体(TORP);(3)12例使用自体软骨。术前及术后2个月和3年进行纯音听力测定(PTA)。在仅表现为镫骨上部结构的24例患者中,14例行PORP听骨成形术,12例行软骨短柱听骨成形术(SCC)。在仅镫骨足板活动的8例患者中,6例行TORP听骨成形术,仅2例行长柱软骨听骨成形术(LCC)。纯音听力测定术前平均气导阈值(AC)在PORP组为45.47dB,TORP组为66.10dB,SCC组为49.15dB,LCC组为59.15dB。术后2个月AC分别为PORP组27.37dB,TORP组45.83dB,SCC组29.99dB,LCC组39.15dB。术后2个月气骨导差(ABG)在PORP组为19.05dB,TORP组为20dB,SCC组为20.32dB,LCC组为39.15dB,3年后变化不大。术后4 - 8年,3例PORP和4例TORP出现假体脱出。4例失访。软骨听骨成形术未出现假体脱出。经耳道内镜自体软骨听骨成形术在修复胆脂瘤疾病听骨方面显示出与钛质假体相当的令人鼓舞的结果。