Agrawal Vikas K, Kodur Swati, Jha Raghav Hira
Speciality ENT Hospital, Thakur Complex, 90 Feet Road, Kandivali East, Mumbai, 400101 India.
Indian J Otolaryngol Head Neck Surg. 2019 Mar;71(1):60-65. doi: 10.1007/s12070-018-1513-2. Epub 2018 Oct 16.
The present study aimed at reporting the incidence of Salpingopharyngeal Fold (SPF) hypertrophy on Drug Induced Sleep Endoscopy (DISE) in patients with Obstructive Sleep Apnoea (OSA, validate a grading system and analyse the impact of various grades on the clinical presentation while ascertaining its relation with Apnoea-Hypopnoea Index (AHI). A retrospective analysis of 169 patients with polysomnographic confirmation of obstructive sleep apnoea has been done in the study. The DISE video data of 169 patients was evaluated by two ENT surgeons individually and they graded the hypertrophy of the fold as Grade 0 being normal anatomy, Grade 1 being hypertrophy causing partial obstruction and Grade 2 being hypertrophy causing complete obstruction of lateral pharyngeal wall. It was found that the presence of SPF hypertrophy independently adds considerably to the severity of the obstruction, attributing to lateral collapse at the upper retropalatal level and also significantly increases AHI. It is thus advised to consider the grade of SPF hypertrophy while surgically planning the management of patients with OSA.
本研究旨在报告阻塞性睡眠呼吸暂停(OSA)患者药物诱导睡眠内镜检查(DISE)中咽鼓管咽襞(SPF)肥大的发生率,验证一种分级系统,并分析不同级别对临床表现的影响,同时确定其与呼吸暂停低通气指数(AHI)的关系。本研究对169例经多导睡眠图证实为阻塞性睡眠呼吸暂停的患者进行了回顾性分析。169例患者的DISE视频数据由两名耳鼻喉科医生分别评估,他们将咽襞肥大分级为:0级为正常解剖结构,1级为肥大导致部分阻塞,2级为肥大导致咽侧壁完全阻塞。研究发现,SPF肥大的存在独立地显著增加了阻塞的严重程度,导致腭后上部水平的侧方塌陷,并且也显著增加AHI。因此,建议在手术规划OSA患者的治疗时考虑SPF肥大的分级。