Blas B L, Cabrera B D, Santos A T, Noseñas J S
Southeast Asian J Trop Med Public Health. 1986 Mar;17(1):67-70.
As a sequence to a cross-sectional study on the clinical gradient of the disease by Pesigan et al., (1965) a follow-up of the subjects in that study was made after 12 years. Of the 135 untreated cases followed up, 23 (17.04%) died from various causes of which 12 (8.89%) had signs and symptoms attributable to schistosomiasis as the immediate cause or one of the main causes of death. This occurred in 1 to 11 years with an average of 5 years, which corresponds roughly to 1.78% of the infected cases per year. This is considered a conservative estimate because in the other deaths due to other diseases, schistosomiasis is a contributory cause. A diminishing severity of the disease was observed among the surviving patients which could imply that they must have developed some degree of immunity to the disease.
作为佩西根等人（1965年）关于该疾病临床梯度的横断面研究的后续研究，对该研究中的受试者进行了12年后的随访。在随访的135例未经治疗的病例中，23例（17.04%）死于各种原因，其中12例（8.89%）有可归因于血吸虫病的体征和症状，为直接死因或主要死因之一。这发生在1至11年，平均为5年，大致相当于每年感染病例的1.78%。这被认为是一个保守的估计，因为在其他因其他疾病导致的死亡中，血吸虫病是一个促成因素。在存活患者中观察到疾病严重程度的降低，这可能意味着他们一定已经对该疾病产生了某种程度的免疫力。
