Bruserud O, Degré M, Thorsby E
Acta Pathol Microbiol Immunol Scand C. 1986 Apr;94(2):51-5. doi: 10.1111/j.1699-0463.1986.tb02089.x.
Interleukin 2 (IL 2) production, expression of IL 2-receptors and interferon (IFN) production in vitro by human mononuclear cells stimulated with inactivated mumps-virus antigen and phytohaemagglutinin (PHA, a T lymphocyte mitogen) were characterized. The detectable level of the T-cell lymphokine IL 2 in culture supernatants peaked after 18-24 hours for PHA stimulation and after 48 hours for mumps stimulation. The expression of IL 2 receptors was maximal on day 3 of PHA stimulation and days 5-6 of mumps stimulation. The IFN-level in culture supernatants showed only small variations during the culture period, both for mumps- and PHA-stimulated cultures, and IFN-gamma was detected in both cultures.
对用灭活腮腺炎病毒抗原和植物血凝素（PHA，一种T淋巴细胞有丝分裂原）刺激的人单核细胞在体外产生白细胞介素2（IL-2）、IL-2受体的表达以及干扰素（IFN）的产生进行了表征。培养上清液中可检测到的T细胞淋巴因子IL-2水平在PHA刺激后18 - 24小时达到峰值，腮腺炎刺激后48小时达到峰值。IL-2受体的表达在PHA刺激的第3天以及腮腺炎刺激的第5 - 6天达到最大值。对于腮腺炎和PHA刺激的培养物，培养上清液中的IFN水平在培养期间仅显示出微小变化，并且在两种培养物中均检测到IFN-γ。
